Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679838 | 0.74 | CTSC (0.41) | CYP3A4ENPP3ENPP1ENPP2ALDH1A1 | |
| SCHEMBL5590915 | 0.72 | ENPP3 (0.35) | CYP3A4CYP2C19KCNA5ENPP3ENPP1 | |
| SCHEMBL5592370 | 0.72 | ENPP3 (0.35) | CYP3A4CYP2C19KCNA5ENPP3ENPP1 | |
| SCHEMBL20833342 | 0.66 | GBA1 (0.36) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5506318 | 0.66 | CTSC (0.42) | CYP3A4ALDH1A1CTSC | |
| SCHEMBL28679839 | 0.66 | CTSC (0.42) | CYP3A4ALDH1A1CTSC | |
| SCHEMBL9332822 | 0.65 | LMNA (0.43) | FKBP1APKM | |
| SCHEMBL3930177 | 0.64 | TSHR (0.47) | FKBP1AALDH1A1CTSC | |
| SCHEMBL1415100 | 0.64 | TSHR (0.47) | FKBP1AALDH1A1CTSC | |
| SCHEMBL20833507 | 0.64 | CYP1A2 (0.36) | CYP3A4SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017894-A2 | PREPARATION OF NOVEL CRYSTALLINE η(ETA) FORM OF PERINDOPRIL ERBUMINE | ARCH PHARMALABS LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007017893-A2 | PREPARATION OF NOVEL CRYSTALLINE FORM OF PERINDOPRIL ERBUMINE MONOHYDRATE | ARCH PHARMALABS LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |