Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592370 | 1.00 | ENPP3 (0.35) | ENPP3ENPP1ENPP2HTR6CYP3A4 | |
| SCHEMBL28679838 | 0.73 | CTSC (0.41) | ENPP3ENPP1ENPP2CYP3A4ALDH1A1 | |
| SCHEMBL5591313 | 0.72 | CYP3A4 (0.34) | ENPP3ENPP1ENPP2CYP3A4CYP2C19 | |
| SCHEMBL4781916 | 0.64 | SIRT2 (0.40) | HPGDALDH1A1LMNA | |
| SCHEMBL10637725 | 0.63 | ALDH1A1 (0.60) | CYP3A4CYP2C19ALDH1A1LMNAPOLB | |
| SCHEMBL28679839 | 0.63 | CTSC (0.42) | CYP3A4ALDH1A1LMNAEPHX2POLB | |
| SCHEMBL5506318 | 0.63 | CTSC (0.42) | CYP3A4ALDH1A1LMNAEPHX2POLB | |
| SCHEMBL9332822 | 0.62 | LMNA (0.43) | LMNAMEN1KMT2A | |
| SCHEMBL1415100 | 0.61 | TSHR (0.47) | HPGDALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL3930177 | 0.61 | TSHR (0.47) | HPGDALDH1A1LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017894-A2 | PREPARATION OF NOVEL CRYSTALLINE η(ETA) FORM OF PERINDOPRIL ERBUMINE | ARCH PHARMALABS LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |