SCHEMBL55915

SCHEMBL55915

CC(=O)c1ccc(Br)cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.58
MAOB P27338 5/20 0.58
HPGD P15428 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP3A4 P08684 1/20 0.55
MAPK1 P28482 1/20 0.55
ALOX15 P16050 2/20 0.52
CES2 O00748 1/20 0.52
GALR3 O60755 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CASP1 P29466 1/20 0.52
CYP2C19 P33261 1/20 0.52
PTGDR2 Q9Y5Y4 1/20 0.46
PRKDC P78527 1/20 0.45
GSTA1 P08263 1/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HTT P42858 1/20 0.44
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28768383 1.00 MAOA (0.58) MAOAMAOBHPGDALDH1A1CYP3A4
SCHEMBL29433676 1.00 MAOA (0.58) MAOAMAOBHPGDALDH1A1CYP3A4
SCHEMBL309016 0.83 HPGD (0.69) MAOAMAOBHPGDALDH1A1ALOX15
(Chloromethyl)Benzene SCHEMBL28025730 0.82 MAOB (0.54) MAOAMAOBHPGDPTGDR2
SCHEMBL30864269 0.82 MAOA (0.53) MAOAMAOBHPGDALDH1A1ALOX15
SCHEMBL10357446 0.82 CES2 (0.52) MAOAMAOBHPGDALDH1A1ALOX15
SCHEMBL29530881 0.80 L3MBTL1 (0.47) MAOAMAOBHPGDALDH1A1MAPK1
SCHEMBL467470 0.80 ALDH1A1 (0.61) HPGDALDH1A1CYP3A4MAPK1ALOX15
SCHEMBL1312703 0.80 L3MBTL1 (0.47) MAOAMAOBHPGDALDH1A1MAPK1
SCHEMBL5888486 0.79 HPGD (0.64) MAOAMAOBHPGDALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178385-B Coumarin hemicyanine dye with structural rigidity, and preparation method and application thereof 山西大学 2025-01-28 CN claimed
CN-114835698-B (diphenylamino) phenyl flavonoid fluorescent probe for detecting cysteine and preparation method thereof 南京林业大学 2024-03-15 CN claimed
CN-114751870-B 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof 贵州医科大学 2023-10-20 CN claimed
CN-116515782-A Amine dehydrogenase mutant and application thereof in chiral amine alcohol compound synthesis 中国科学院天津工业生物技术研究所 2023-08-01 CN claimed
CN-116178385-A Coumarin hemicyanine dye with structural rigidity, and preparation method and application thereof 山西大学 2023-05-30 CN claimed
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN claimed
CN-114835698-A (diphenylamino) phenyl flavonoid fluorescent probe for detecting cysteine and preparation method thereof 南京林业大学 2022-08-02 CN claimed
CN-114751870-A 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof 贵州医科大学 2022-07-15 CN claimed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN claimed
CN-111548280-B Fluorescent probe for rapidly identifying mercury and methyl mercury as well as preparation method and application thereof 北京师范大学 2021-04-20 CN claimed
CN-103936631-B A kind of Biphenyl carbamide compound containing oximido and its preparation method and application XI'AN JIAOTONG UNIVERSITY (CN) 2015-08-05 CN claimed
CN-103288684-B Biphenyl carbamide compound with antineoplastic activity and preparation method thereof UNIV XI AN JIAOTONG 2014-12-10 CN claimed
CN-103936631-A Oximido diphenyl urea compound as well as preparation method and application thereof UNIV XI AN JIAOTONG 2014-07-23 CN claimed
CN-103288684-A Biphenyl carbamide compound with antineoplastic activity and preparation method thereof UNIV XI AN JIAOTONG 2013-09-11 CN claimed
US-12630561-B2 Tricyclic derivatives inhibitor, preparation method, and applications thereof JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2026-05-19 US disclosed
US-20260125378-A2 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
EP-4735452-A2 HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS PROTEIN Merck Patent GmbH (DE) 2026-05-06 EP disclosed
WO-1995004046-A1 COMPOUNDS AS PDE IV AND TNF INHIBITORS RHONE-POULENC RORER LIMITED (GB) 1995-02-09 WO disclosed
US-5332757-A Enzyme inhibitors ZENECA LIMITED (GB) 1994-07-26 US disclosed
EP-0555068-A1 Oxime derivatives as 5-lipoxygenase inhibitors ZENECA LIMITED (GB) 1993-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125378-A2 Heterocyclic Compounds NFATC1, CD4, MALT1 MAOA 2893/4885MAOB 2174/4885HPGD 1265/4885
US-12630561-B2 Tricyclic derivatives inhibitor, preparation method, and applications thereof PIK3CA, PIK3R1, PIK3CD MAOA 2181/4885MAOB 1702/4885HPGD 1915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.