SCHEMBL467470

SCHEMBL467470

O=C(O)c1ccc(Br)cc1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
TSHR P16473 1/20 0.61
KDM4E B2RXH2 6/20 0.57
PTPN1 P18031 3/20 0.57
MAPT P10636 2/20 0.57
CYP3A4 P08684 1/20 0.57
GAA P10253 1/20 0.57
ESR2 Q92731 1/20 0.57
GLA P06280 1/20 0.55
HPGD P15428 5/20 0.54
CYP2C9 P11712 2/20 0.54
CES2 O00748 1/20 0.54
GALR3 O60755 1/20 0.54
CYP1A2 P05177 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20505340 0.83 CES2 (0.55) ALDH1A1CA12CA1CA2CA7
SCHEMBL30352763 0.82 CYP2C9 (0.72) ALDH1A1CA12CA1CA2CA7
SCHEMBL129669 0.82 CYP2C9 (0.72) ALDH1A1CA12CA1CA2CA7
SCHEMBL618056 0.81 KDM4E (0.65) KDM4EGLAHPGDCYP2C9CES2
SCHEMBL9487167 0.80 CYP2C9 (0.69) ALDH1A1CA12CA1CA2CA7
SCHEMBL28768383 0.80 MAOA (0.58) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL9864432 0.80 ALOX15 (0.52) ALDH1A1CA12CA1CA2CA7
SCHEMBL13740129 0.80 DGAT1 (0.62) ALDH1A1TSHRKDM4EMAPTGAA
SCHEMBL55915 0.80 MAOA (0.58) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL29433676 0.80 MAOA (0.58) ALDH1A1KDM4EMAPTCYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 660 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US claimed
EP-4501896-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND Kao Corporation (JP) 2025-02-05 EP claimed
CN-118973990-A Process for producing cyclic diketone compound 花王株式会社 2024-11-15 CN claimed
WO-2023189722-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND 花王株式会社 2023-10-05 WO claimed
CN-113087683-B Nitrogen-substituted benzothiazolinone XOR/URAT1 dual inhibitor and preparation method and application thereof 华南理工大学 2022-04-22 CN claimed
CN-110028443-B Preparation method of tricyclic compound drug intermediate for regulating FXR activity 济南周行医药科技有限公司 2022-03-04 CN claimed
CN-113816940-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-21 CN claimed
CN-113754634-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-07 CN claimed
CN-113087683-A Nitrogen-substituted benzothiazolinone XOR/URAT1 dual inhibitor and preparation method and application thereof 华南理工大学 2021-07-09 CN claimed
CN-110028443-A A kind of preparation method adjusting the active tricyclic compound class pharmaceutical intermediate of FXR 济南周行医药科技有限公司 2019-07-19 CN claimed
CN-105418404-A Synthesis method of 2-hydroxyl-4-bromobenzoic acid DING YUQIN 2016-03-23 CN claimed
EP-0218689-B1 ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES AND COMPOSITIONS THE UPJOHN COMPANY (US) 1990-08-01 EP claimed
EP-0263209-A2 Anthelmintic quinolinyl acylhydrazones THE UPJOHN COMPANY (US) 1988-04-13 EP claimed
WO-1986005982-A3 ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1987-04-23 WO claimed
EP-0218689-A1 ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES AND COMPOSITIONS. UPJOHN CO (US) 1987-04-22 EP claimed
WO-1986005982-A2 ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS UPJOHN CO (US) 1986-10-23 WO claimed
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2026-05-07 US disclosed
US-20260107972-A1 AEROSOL GENERATING GEL MATERIAL COMPRISING A SUBSTITUTED 3-(1 METHYLPYRROLIDIN-2-YL)PYRIDINE RAI STRATEGIC HOLDINGS INC (US) 2026-04-23 US disclosed
WO-1986005982-A2 ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS UPJOHN CO (US) 1986-10-23 WO disclosed
US-4006243-A FUNGICIDE, BACTERICIDE, YEAST SCHERING AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND HSD17B7, HSD17B12, BCKDK ALDH1A1 699/4885CA12 2616/4885CA1 2942/4885
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, MALT1, BCL6 ALDH1A1 56/4885CA12 74/4885CA1 31/4885
US-20260107972-A1 AEROSOL GENERATING GEL MATERIAL COMPRISING A SUBSTITUTED 3-(1 METHYLPYRROLIDIN-2-YL)PYRIDINE ACTN1, ARPC3, ARPC4 ALDH1A1 1502/4885CA12 3688/4885CA1 4197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.