Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800901 | 0.76 | KIF11 (0.34) | TRPV1MPIPHOSPHO1CYP19A1SCN9A | |
| SCHEMBL17537378 | 0.66 | GSK3A (0.59) | GSK3AGSK3BTRPV1MPIPHOSPHO1 | |
| SCHEMBL1451027 | 0.66 | BRPF1 (0.50) | — | |
| SCHEMBL25042634 | 0.66 | KDM4E (0.50) | GSK3AGSK3BTRPV1MPIPHOSPHO1 | |
| SCHEMBL30039561 | 0.64 | L3MBTL1 (0.59) | GSK3AGSK3BTRPV1MPIPHOSPHO1 | |
| SCHEMBL859629 | 0.64 | L3MBTL1 (0.59) | GSK3AGSK3BTRPV1MPIPHOSPHO1 | |
| SCHEMBL30171463 | 0.64 | TRPV1 (0.44) | GSK3AGSK3BTRPV1MPIPHOSPHO1 | |
| SCHEMBL14933491 | 0.64 | TRPV1 (0.51) | GSK3AGSK3BTRPV1MPIPHOSPHO1 | |
| SCHEMBL25042657 | 0.63 | TEAD1 (0.51) | GSK3BPPARGPPARACFTRSCN9A | |
| SCHEMBL1447792 | 0.63 | BACE1 (0.37) | NOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076104-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2007-07-05 | — | — | WO | disclosed |