Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541844 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAALDH1A1LMNAOPRM1 | |
| SCHEMBL2696963 | 0.73 | CYP2B6 (0.66) | SMN1; SMN2GAAALDH1A1LMNAOPRM1 | |
| SCHEMBL18901958 | 0.73 | OPRM1 (0.44) | SMN1; SMN2GAAALDH1A1LMNAOPRM1 | |
| SCHEMBL11541847 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAALDH1A1LMNAOPRM1 | |
| SCHEMBL3312757 | 0.70 | SMN1; SMN2 (0.58) | SMN1; SMN2GAAALDH1A1LMNAOPRM1 | |
| SCHEMBL12613218 | 0.70 | ALDH1A1 (0.42) | SMN1; SMN2GAAALDH1A1LMNAPOLB | |
| SCHEMBL8904963 | 0.69 | LMNA (0.48) | SMN1; SMN2GAAALDH1A1LMNAOPRM1 | |
| SCHEMBL435727 | 0.69 | LMNA (0.48) | SMN1; SMN2GAAALDH1A1LMNAOPRM1 | |
| SCHEMBL26162956 | 0.67 | GAA (0.42) | SMN1; SMN2GAAALDH1A1LMNAOPRM1 | |
| SCHEMBL9340359 | 0.67 | CYP2C19 (0.42) | ALDH1A1LMNAMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076104-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2007-07-05 | — | — | WO | disclosed |