Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26162956 | 0.81 | GAA (0.42) | OPRM1OPRD1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9079796 | 0.74 | MAPT (0.44) | SMN1; SMN2GAAALDH1A1FKBP1ALMNA | |
| SCHEMBL4541997 | 0.73 | KCNA5 (0.48) | OPRM1OPRD1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL5591971 | 0.73 | SMN1; SMN2 (0.47) | OPRM1OPRD1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL11541844 | 0.70 | SMN1; SMN2 (0.54) | OPRM1OPRD1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL12613218 | 0.70 | ALDH1A1 (0.42) | SMN1; SMN2GAAALDH1A1FKBP1ALMNA | |
| SCHEMBL18889556 | 0.70 | OPRM1 (0.60) | OPRM1OPRD1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2696963 | 0.70 | CYP2B6 (0.66) | OPRM1OPRD1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9681172 | 0.70 | SMN1; SMN2 (0.50) | OPRM1OPRD1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8904963 | 0.69 | LMNA (0.48) | OPRM1OPRD1SMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |