Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.73 |
| ▸ | HTR1A | P08908 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | DRD5 | P21918 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592140 | 0.99 | HTR7 (0.71) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL5592137 | 0.89 | HTR1A (0.57) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL5592292 | 0.88 | HTR1A (0.56) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL5592204 | 0.87 | HTR1A (0.55) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6072935 | 0.86 | HTR7 (0.54) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL5592295 | 0.86 | HTR7 (0.97) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6072733 | 0.85 | HTR7 (0.53) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL5592269 | 0.85 | HTR7 (0.95) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6017582 | 0.84 | HTR7 (1.00) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL5592245 | 0.84 | HTR1A (0.52) | HTR7HTR1AMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |