Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592291 | 0.88 | BRD9 (0.38) | SLC6A2SLC6A4SLC6A3TNK2KDM1A | |
| SCHEMBL5592191 | 0.82 | HSD11B1 (0.36) | ELANECHIA | |
| SCHEMBL5592317 | 0.80 | ALDH1A1 (0.37) | CCNT1CDK4CCND1CCND3CDK7 | |
| SCHEMBL5592384 | 0.79 | CHIA (0.35) | ELANECHIACCNT1CDK4CCND1 | |
| SCHEMBL5599159 | 0.79 | ELANE (0.35) | ELANECHIA | |
| SCHEMBL5808001 | 0.71 | ACACB (0.34) | CDK4CCND1CCND3CDK6TNK2 | |
| SCHEMBL5592307 | 0.68 | HSD11B1 (0.36) | ELANECHIA | |
| SCHEMBL5592320 | 0.67 | CHIA (0.39) | ELANECHIA | |
| SCHEMBL25925455 | 0.67 | CHIA (0.58) | ELANECHIAHRH4HTR2C | |
| SCHEMBL5166529 | 0.67 | CHIA (0.43) | ELANECHIAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057742-A2 | NOVEL PIPERAZINONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |