Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 9/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.38 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.34 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592285 | 0.88 | ELANE (0.35) | SLC6A2SLC6A4SLC6A3KDM1ATNK2 | |
| SCHEMBL5592317 | 0.86 | ALDH1A1 (0.37) | HTR1ATNK2DRD2HTR2A | |
| SCHEMBL5592389 | 0.79 | DRD2 (0.39) | BRD9BRD4BRPF1BRD7SLC6A2 | |
| SCHEMBL5599213 | 0.79 | SLC6A2 (0.40) | BRD9BRD4BRPF1BRD7SLC6A2 | |
| SCHEMBL5592325 | 0.76 | NCF1 (0.36) | BRD9BRD4BRPF1BRD7SLC6A2 | |
| SCHEMBL5592318 | 0.76 | MEN1 (0.36) | BRD9BRD4BRPF1BRD7SLC6A2 | |
| SCHEMBL5592174 | 0.74 | SLC6A2 (0.35) | BRD9BRD4BRPF1SLC6A2SLC6A4 | |
| SCHEMBL5808001 | 0.73 | ACACB (0.34) | KDM1ATNK2HTR2CMEN1KMT2A | |
| SCHEMBL1737840 | 0.71 | WDR5 (0.40) | BRD9BRD4BRPF1BRD7 | |
| SCHEMBL5606425 | 0.71 | WDR5 (0.40) | BRD9BRD4BRPF1BRD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057742-A2 | NOVEL PIPERAZINONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |