Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 7/20 | 0.35 |
| ▸ | DRD3 | P35462 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | GLS | O94925 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5599207 | 0.99 | HPGD (0.35) | HPGDDRD2DRD3HTR2AHTR1A | |
| SCHEMBL5330305 | 0.83 | ATM (0.42) | HPGDDRD2DRD3HTR2AHTR1A | |
| SCHEMBL5815641 | 0.72 | RAB9A (0.47) | HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL5592226 | 0.72 | HTR1A (0.43) | DRD2DRD3HTR1ADRD4SMN1; SMN2 | |
| SCHEMBL5592381 | 0.67 | CHRM1 (0.44) | ALDH1A1 | |
| SCHEMBL5592133 | 0.65 | CHRM1 (0.52) | DRD2HTR2AALDH1A1 | |
| SCHEMBL5592138 | 0.60 | MEN1 (0.47) | SMN1; SMN2ALDH1A1TP53TSHRPOLB | |
| SCHEMBL18924415 | 0.60 | ALDH1A1 (0.51) | HPGDSMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL18389931 | 0.60 | SMN1; SMN2 (0.50) | HPGDDRD2DRD3HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL5592211 | 0.59 | MEN1 (0.46) | SMN1; SMN2ALDH1A1TP53TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |