Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5592864 | 0.92 | CTSS (0.47) | CTSSCTSKCTSLCTSBMELK | |
| SCHEMBL5592852 | 0.91 | CTSL (0.43) | CTSSCTSKCTSLCTSBMELK | |
| Trifluoroacetic Acid SCHEMBL5592645 | 0.91 | CTSS (0.47) | CTSSCTSKCTSLCTSBMELK | |
| SCHEMBL5592704 | 0.91 | CTSS (0.59) | CTSSCTSKCTSLCTSBMELK | |
| SCHEMBL5592894 | 0.88 | CTSL (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5592735 | 0.88 | CTSS (0.49) | CTSSCTSKCTSLCTSBMELK | |
| SCHEMBL5592632 | 0.87 | CTSL (0.45) | CTSSCTSKCTSLCTSBMELK | |
| SCHEMBL5592803 | 0.86 | CTSS (0.41) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5592660 | 0.86 | CTSS (0.49) | CTSSCTSKCTSLCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5592759 | 0.86 | CTSL (0.47) | CTSSCTSKCTSLCTSBMELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |