Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592691 | 0.88 | CTSS (0.49) | CTSLCTSBCTSSCTSK | |
| SCHEMBL5593156 | 0.84 | CTSL (0.43) | CTSLCTSBCTSSCTSKFNTA | |
| SCHEMBL5592803 | 0.83 | CTSS (0.41) | CTSLCTSBCTSSCTSKPRKAA2 | |
| SCHEMBL5592735 | 0.83 | CTSS (0.49) | CTSLCTSBCTSSCTSK | |
| SCHEMBL8236817 | 0.83 | CTSL (0.65) | CTSLCTSBCTSSCTSKACVR1 | |
| SCHEMBL5592660 | 0.83 | CTSS (0.49) | CTSLCTSBCTSSCTSKCHRM2 | |
| Trifluoroacetic Acid SCHEMBL5592759 | 0.83 | CTSL (0.47) | CTSLCTSBCTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL5592942 | 0.82 | CTSS (0.47) | CTSLCTSBCTSSCTSKCHRM4 | |
| Trifluoroacetic Acid SCHEMBL5592645 | 0.81 | CTSS (0.47) | CTSLCTSBCTSSCTSKACVR1 | |
| Trifluoroacetic Acid SCHEMBL5592864 | 0.81 | CTSS (0.47) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |