Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.41 |
| ▸ | CTSK | P43235 | 8/20 | 0.41 |
| ▸ | CTSL | P07711 | 6/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592899 | 0.91 | CHEK1 (0.38) | CTSSCTSKCTSLCTSBCHEK1 | |
| SCHEMBL5592691 | 0.86 | CTSS (0.49) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5592894 | 0.83 | CTSL (0.45) | CTSSCTSKCTSLCTSBCHRM4 | |
| SCHEMBL5592660 | 0.82 | CTSS (0.49) | CTSSCTSKCTSLCTSBCHRM4 | |
| SCHEMBL8242605 | 0.82 | CTSS (0.60) | CTSSCTSKCTSLCTSBCHEK1 | |
| SCHEMBL5593156 | 0.80 | CTSL (0.43) | CTSSCTSKCTSLCTSBPRKAA2 | |
| SCHEMBL5592735 | 0.80 | CTSS (0.49) | CTSSCTSKCTSLCTSB | |
| Trifluoroacetic Acid SCHEMBL5592645 | 0.80 | CTSS (0.47) | CTSSCTSKCTSLCTSB | |
| Trifluoroacetic Acid SCHEMBL5592864 | 0.79 | CTSS (0.47) | CTSSCTSKCTSLCTSB | |
| Trifluoroacetic Acid SCHEMBL5592759 | 0.78 | CTSL (0.47) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |