Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 11/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 6/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 6/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 6/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 6/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 6/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5592942 | 0.85 | CTSS (0.47) | CTSLCTSBCTSSCTSKCXCR3 | |
| SCHEMBL5592691 | 0.85 | CTSS (0.49) | CTSLCTSBCTSSCTSKMCHR1 | |
| SCHEMBL5592894 | 0.84 | CTSL (0.45) | CTSLCTSBCTSSCTSKPRKAA2 | |
| Trifluoroacetic Acid SCHEMBL5592645 | 0.84 | CTSS (0.47) | CTSLCTSBCTSSCTSKMCHR1 | |
| Trifluoroacetic Acid SCHEMBL5592759 | 0.84 | CTSL (0.47) | CTSLCTSBCTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL5592864 | 0.83 | CTSS (0.47) | CTSLCTSBCTSSCTSKCYP3A4 | |
| SCHEMBL3168730 | 0.80 | CTSL (0.44) | CTSLCTSBCTSSCTSKPRKAA2 | |
| SCHEMBL5592803 | 0.80 | CTSS (0.41) | CTSLCTSBCTSSCTSKPRKAA2 | |
| SCHEMBL5592735 | 0.80 | CTSS (0.49) | CTSLCTSBCTSSCTSKMCHR1 | |
| SCHEMBL5592660 | 0.80 | CTSS (0.49) | CTSLCTSBCTSSCTSKPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |