Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5592964

CC(C)Cc1ccccc1C(=O)NN.O=C(O)C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 2/20 0.42
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 2/20 0.40
HPGD P15428 2/20 0.40
EPHX2 P34913 1/20 0.39
PPARG P37231 1/20 0.39
CAPN1 P07384 1/20 0.39
KDM4E B2RXH2 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
ESR1 P03372 1/20 0.39
KCNH2 Q12809 1/20 0.39
PADI1 Q9ULC6 1/20 0.38
PADI3 Q9ULW8 1/20 0.38
PADI4 Q9UM07 1/20 0.38
P2RX7 Q99572 1/20 0.38
GABRA1 P14867 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5593166 0.89 CTSD (0.50) CTSDALDH1A1MEN1KMT2ALMNA
Trifluoroacetic Acid SCHEMBL4611875 0.76 MLYCD (0.43) ALDH1A1MEN1KMT2AHPGDCAPN1
SCHEMBL13670100 0.76 KMT2A (0.50) ALDH1A1MEN1KMT2ALMNAHPGD
SCHEMBL157592 0.74 FOLH1 (0.53) ALDH1A1MEN1KMT2ALMNAHPGD
Trifluoroacetic Acid SCHEMBL4598303 0.74 GAA (0.47) ALDH1A1LMNAHPGDCAPN1KDM4E
SCHEMBL17799517 0.73 FOLH1 (0.52) ALDH1A1MEN1KMT2ALMNAHPGD
SCHEMBL1002816 0.73 HTT (0.50) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL8087714 0.73 GABRA1 (0.48) ALDH1A1MEN1KMT2ALMNAHPGD
SCHEMBL31112114 0.73 CTSD (0.46) CTSDALDH1A1MEN1KMT2ALMNA
SCHEMBL28801221 0.72 CTSD (0.52) CTSDALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007025775-A2 CYSTEINE PROTEASE INHIBITORS GLAXO GROUP LIMITED (GB) 2007-03-08 WO claimed