Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22165795 | 0.82 | NOS3 (0.48) | NOS3NOS1NOS2KDM4EKMT2A | |
| SCHEMBL25194211 | 0.81 | DHFR (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL30402750 | 0.81 | DHFR (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL21591671 | 0.79 | ALDH1A1 (0.34) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL25198432 | 0.74 | NOS2 (0.37) | NOS3NOS1NOS2KDM4EKMT2A | |
| SCHEMBL5593300 | 0.74 | POLB (0.39) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL3343795 | 0.73 | KDM4E (0.36) | NOS3NOS1NOS2KDM4EKMT2A | |
| SCHEMBL25373535 | 0.72 | UHRF1 (0.48) | NOS3NOS1NOS2 | |
| SCHEMBL25370487 | 0.68 | NOS2 (0.35) | NOS3NOS1NOS2KDM4EKMT2A | |
| SCHEMBL30154986 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |