Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.64 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 2/20 | 0.51 |
| ▸ | FYN | P06241 | 6/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503140 | 0.86 | LDHA (0.79) | LDHACYP4F2CYP4A11P4HA1P4HTM | |
| SCHEMBL31243316 | 0.84 | LDHA (0.77) | LDHACYP4F2CYP4A11P4HA1P4HTM | |
| SCHEMBL20730171 | 0.83 | FYN (0.48) | CYP4F2CYP4A11HPGDSFYNKDM1A | |
| SCHEMBL2540857 | 0.83 | ACMSD (0.51) | LDHACYP4F2CYP4A11HPGDSFYN | |
| SCHEMBL5592910 | 0.81 | LDHA (0.67) | LDHAP4HA1P4HTMHPGDSSMN1; SMN2 | |
| SCHEMBL6562815 | 0.80 | LDHA (0.70) | LDHACYP4F2CYP4A11P4HA1P4HTM | |
| SCHEMBL5519447 | 0.79 | KMO (0.63) | PTGER4KDM5AKDM2BKDM4CKDM5B | |
| SCHEMBL505455 | 0.79 | LDHA (1.00) | LDHAP4HA1P4HTMHPGDSSMN1; SMN2 | |
| SCHEMBL2560542 | 0.79 | LDHA (0.68) | LDHAP4HA1P4HTMHPGDSFYN | |
| SCHEMBL1543156 | 0.79 | HPGDS (0.76) | LDHACYP4F2CYP4A11P4HA1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |