Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.46 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593509 | 0.81 | GAA (0.44) | MAPTRAB9AGAAALDH1A1LMNA | |
| SCHEMBL5593513 | 0.81 | GAA (0.44) | MAPTRAB9AGAAALDH1A1LMNA | |
| SCHEMBL14473328 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2MAPTRAB9AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL5593031 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2MAPTRAB9AALDH1A1HTT | |
| SCHEMBL17979844 | 0.77 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTRAB9AGAAKDM4E | |
| SCHEMBL5593426 | 0.75 | GABRA1 (0.43) | SMN1; SMN2MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL5604172 | 0.72 | MAPT (0.49) | SMN1; SMN2MAPTRAB9AGAAKDM4E | |
| SCHEMBL5593369 | 0.70 | ALDH1A1 (0.40) | SMN1; SMN2MAPTRAB9AGAAKDM4E | |
| SCHEMBL31205210 | 0.69 | RAF1 (0.52) | SMN1; SMN2MAPTRAB9ASLC6A5ALDH1A1 | |
| SCHEMBL4020263 | 0.69 | RAB9A (0.57) | SMN1; SMN2MAPTRAB9AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |