Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593509 | 0.82 | GAA (0.44) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL5593513 | 0.82 | GAA (0.44) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL14473328 | 0.79 | ALDH1A1 (0.43) | MAPTKMT2AALDH1A1MEN1HTT | |
| Hydrochloric Acid SCHEMBL5593031 | 0.78 | ALDH1A1 (0.42) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL5593426 | 0.74 | GABRA1 (0.43) | MAPTNPSR1KMT2AALDH1A1MEN1 | |
| SCHEMBL5593350 | 0.72 | SMN1; SMN2 (0.52) | MAPTALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL5593369 | 0.71 | ALDH1A1 (0.40) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL5593372 | 0.70 | KMT2A (0.42) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL5593366 | 0.70 | KMT2A (0.42) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL23613437 | 0.67 | ALDH1A1 (1.00) | MAPTNPSR1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |