SCHEMBL559361

SCHEMBL559361

Cc1cccc(C[Mg]Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.55
IDO1 P14902 2/20 0.48
ACHE P22303 1/20 0.46
HRH3 Q9Y5N1 1/20 0.42
MAOB P27338 2/20 0.41
POLB P06746 3/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
CTBP2 P56545 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
DAO P14920 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5253754 0.78 TAAR1 (0.50) TAAR1IDO1ACHEHRH3MAOB
SCHEMBL933385 0.78 TAAR1 (0.50) TAAR1IDO1ACHEHRH3MAOB
SCHEMBL2291118 0.77 ALDH1A1 (0.35) TAAR1MAPTCYP11B1CYP11B2
SCHEMBL1004527 0.76 TAAR1 (0.57) TAAR1IDO1MAOB
SCHEMBL5247951 0.75 GRIN2D (0.40) TAAR1MEN1KMT2A
SCHEMBL52147 0.75
SCHEMBL30084583 0.75
SCHEMBL31736930 0.74 TAAR1 (0.55) TAAR1IDO1MAOBCYP11B1CYP11B2
SCHEMBL1003357 0.74 TAAR1 (0.55) TAAR1IDO1MAOBMEN1KMT2A
SCHEMBL29459538 0.74 TAAR1 (0.60) TAAR1IDO1ACHEHRH3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO claimed
US-7273948-B2 Process of preparing esters and ethers of probucol and derivatives thereof ATHEROGENICS, INC. (US) 2007-09-25 US claimed
EP-1594824-A4 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF ATHEROGENICS INC (US) 2007-04-04 EP claimed
EP-1594824-A2 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF Atherogenics, Inc. (US) 2005-11-16 EP claimed
US-20040204485-A1 Process of preparing esters and ethers of probucol and derivatives thereof CRABTREE ACQUISITION CO, LLC 2004-10-14 US claimed
WO-2004062622-A2 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF ATHEROGENICS, INC. (US) 2004-07-29 WO claimed
EP-0343182-B1 ALCOHOLS WITH 3-METHYL OR 3,5-DIMETHYL GROUPS, THEIR PRODUCTION AND THEIR USE AS AROMATICS Consortium für elektrochemische Industrie GmbH (DE) 1992-05-06 EP claimed
EP-0343182-A1 ALCOHOLS WITH 3-METHYL OR 3,5-DIMETHYL GROUPS, THEIR PRODUCTION AND THEIR USE AS AROMATICS. CONSORTIUM ELEKTROCHEM IND (DE) 1989-11-29 EP claimed
WO-1988005770-A1 ALCOHOLS WITH 3-METHYL OR 3,5-DIMETHYL GROUPS THEIR PRODUCTION AND THEIR USE AS AROMATICS Consortium für elektrochemische Industrie GmbH (DE) 1988-08-11 WO claimed
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO disclosed
US-12049461-B2 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections GILEAD SCIENCES, INC. (US) 2024-07-30 US disclosed
US-12012475-B2 Method of olefin polymerization using alkane-soluble non-metallocene precatalyst DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-18 US disclosed
CN-112823163-B Alkane soluble non-metallocene precatalyst 陶氏环球技术有限责任公司 2024-04-19 CN disclosed
US-11859031-B2 Alkane-soluble non-metallocene precatalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2024-01-02 US disclosed
US-4968668-A Alcohols having 3-methyl or 3,5-dimethyl or 3,5-dimethylphenyl groups, a process for their preparation and a fragrance composition containing same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1990-11-06 US disclosed
US-4918231-A REACTING A SILYLATED CYANOHYDRIN WITH GRIGNARD REAGENT; TREATING WITH REDUCING AGENT; HYDROLYSIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-17 US disclosed
EP-0170517-B1 PROCESS FOR THE PRODUCTION OF 1,2-AMINO ALCOHOLS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-12-27 EP disclosed
EP-0343182-A1 ALCOHOLS WITH 3-METHYL OR 3,5-DIMETHYL GROUPS, THEIR PRODUCTION AND THEIR USE AS AROMATICS. CONSORTIUM ELEKTROCHEM IND (DE) 1989-11-29 EP disclosed
WO-1988005770-A1 ALCOHOLS WITH 3-METHYL OR 3,5-DIMETHYL GROUPS THEIR PRODUCTION AND THEIR USE AS AROMATICS Consortium für elektrochemische Industrie GmbH (DE) 1988-08-11 WO disclosed
EP-0170517-A2 Process for the production of 1,2-amino alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11859031-B2 Alkane-soluble non-metallocene precatalysts AP1M1, CCNA1, AMY1A TAAR1 526/4885IDO1 1313/4885ACHE 1566/4885
US-12049461-B2 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections NR3C1, NR3C2, NR4A1 TAAR1 319/4885IDO1 1289/4885ACHE 4515/4885
US-20040204485-A1 Process of preparing esters and ethers of probucol and derivatives thereof NR3C2, MGLL, GCG TAAR1 3193/4885IDO1 4697/4885ACHE 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.