Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596291 | 0.71 | OGA (0.51) | MKNK1MKNK2CYP1A2 | |
| SCHEMBL5597057 | 0.70 | HPGD (0.54) | HRH3MEN1MAPTKMT2AHRH4 | |
| SCHEMBL5596716 | 0.70 | ALDH1A1 (0.40) | MEN1ALDH1A1KMT2AHRH4CYP1A2 | |
| SCHEMBL5596570 | 0.67 | KCNH3 (0.41) | ALDH1A1MAPTMKNK1MKNK2CYP1A2 | |
| SCHEMBL13073926 | 0.66 | HRH3 (0.77) | HRH3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5596251 | 0.66 | HPGD (0.45) | HRH3MEN1KMT2AHRH4 | |
| SCHEMBL8963903 | 0.66 | HRH3 (0.73) | HRH3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL26259806 | 0.66 | — | — | |
| SCHEMBL13036472 | 0.65 | HRH3 (0.78) | HRH3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5596807 | 0.65 | LMNA (0.59) | MEN1ALDH1A1MAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |