Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ILK | Q13418 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596411 | 0.86 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL5596495 | 0.83 | LTA4H (0.39) | RAB9ANPC1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL5596256 | 0.82 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL5596674 | 0.79 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2MAPTILK | |
| SCHEMBL5597098 | 0.79 | MAPT (0.49) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL5596747 | 0.78 | CDK1 (0.35) | RAB9ANPC1SMN1; SMN2MAPTILK | |
| SCHEMBL5596406 | 0.77 | ILK (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL5596942 | 0.77 | ILK (0.51) | RAB9ANPC1SMN1; SMN2MAPTILK | |
| SCHEMBL5596500 | 0.77 | ILK (0.58) | ILK | |
| SCHEMBL5596937 | 0.77 | ILK (0.53) | RAB9ANPC1SMN1; SMN2MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |