Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR7 | P34969 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596495 | 0.81 | LTA4H (0.39) | ILKKMT2APOLBHDAC1MEN1 | |
| SCHEMBL5596256 | 0.80 | NPC1 (0.54) | ILKKMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL5596942 | 0.77 | ILK (0.51) | ILKKMT2APOLBRAD52MEN1 | |
| SCHEMBL5596592 | 0.77 | RAB9A (0.36) | ILK | |
| SCHEMBL5596937 | 0.77 | ILK (0.53) | ILKPOLB | |
| SCHEMBL5596939 | 0.77 | NPC1 (0.44) | ILKKMT2AMKNK1MKNK2MEN1 | |
| SCHEMBL5596418 | 0.77 | NPC1 (0.44) | ILKKMT2APOLBMEN1GBA1 | |
| SCHEMBL5596674 | 0.77 | NPC1 (0.44) | ILKKMT2AHTR7 | |
| SCHEMBL5596406 | 0.75 | ILK (0.51) | ILKKMT2APOLBMKNK1MKNK2 | |
| SCHEMBL5596261 | 0.74 | ALDH1A1 (0.44) | ILKMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |