Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | ILK | Q13418 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596942 | 0.81 | ILK (0.51) | ILKNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7144576 | 0.79 | ILK (0.50) | ILKNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL5596256 | 0.78 | NPC1 (0.54) | ILKNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL5596604 | 0.78 | ILK (0.52) | ILKRAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL5596406 | 0.77 | ILK (0.51) | ILKNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL5596285 | 0.76 | KDM4E (0.47) | JAK1PIK3C3NPC1RAB9AKDM4E | |
| SCHEMBL5596674 | 0.74 | NPC1 (0.44) | ILKNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5596495 | 0.74 | LTA4H (0.39) | ILKNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL5596418 | 0.74 | NPC1 (0.44) | ILKNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL5596937 | 0.74 | ILK (0.53) | ILKNPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |