Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596604 | 0.85 | ILK (0.52) | ILKRAB9AACP1IRAK4TP53 | |
| SCHEMBL5596942 | 0.80 | ILK (0.51) | ILKGAARAB9AKDM4ENPC1 | |
| SCHEMBL5596758 | 0.79 | QPCT (0.41) | ILKRAB9AKDM4ENPC1KMT2A | |
| SCHEMBL5596256 | 0.77 | NPC1 (0.54) | ILKRAB9AKDM4ENPC1LMNA | |
| SCHEMBL5596406 | 0.76 | ILK (0.51) | ILKGAARAB9AKDM4ENPC1 | |
| SCHEMBL4948593 | 0.74 | MAPK8 (0.55) | ILKGAARAB9ANPC1KMT2A | |
| SCHEMBL5596418 | 0.73 | NPC1 (0.44) | ILKGAARAB9AKDM4ENPC1 | |
| SCHEMBL5596937 | 0.73 | ILK (0.53) | ILKGAARAB9AKDM4ENPC1 | |
| SCHEMBL5596495 | 0.73 | LTA4H (0.39) | ILKRAB9AKDM4ENPC1POLB | |
| SCHEMBL5596674 | 0.73 | NPC1 (0.44) | ILKRAB9ANPC1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-B1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS (AN) | 2003-11-12 | — | — | EP | disclosed |