SCHEMBL5597376

SCHEMBL5597376

O=S(=O)(O)c1ccc(Cc2ccccc2Br)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.55
CA1 P00915 12/20 0.55
CA9 Q16790 11/20 0.55
CA12 O43570 9/20 0.55
TSHR P16473 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CA14 Q9ULX7 2/20 0.45
ALDH1A1 P00352 1/20 0.42
NT5E P21589 1/20 0.42
POLB P06746 1/20 0.41
CYP2D6 P10635 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
LMNA P02545 1/20 0.39
ACHE P22303 1/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
IDO1 P14902 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28353192 0.81 TSHR (0.47) CA2CA1CA9TSHRSMN1; SMN2
SCHEMBL780161 0.79 CA1 (0.47) CA2CA1CA9TSHRSMN1; SMN2
SCHEMBL3151100 0.77 TSHR (0.62) CA2CA1CA9CA12TSHR
SCHEMBL9619529 0.77 LMNA (0.56) CA2CA1CA9CA12TSHR
SCHEMBL30117340 0.76 KEAP1 (0.64) CA2CA1CA9CA12TAAR1
Hydrochloric Acid SCHEMBL7261261 0.75 LMNA (0.54) CA2CA1CA9CA12TSHR
SCHEMBL423302 0.75 HTR2A (0.56) SMN1; SMN2TAAR1IDO1
Benzene SCHEMBL28195073 0.75 HTR2A (0.56) SMN1; SMN2TAAR1IDO1
Benzylamine SCHEMBL27648243 0.74 CA1 (0.54) CA2CA1CA9CA12TSHR
SCHEMBL10692906 0.74 CA2 (0.61) CA2CA1CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970937-B1 POLYMER GEL AND PROCESS FOR THE ACTIVATION OF ACTIVE HYDROGEN COMPOUNDS NIPPON CATALYTIC CHEM IND (JP) 2007-07-04 EP disclosed
US-7094853-B2 Crosslinked polymer, method for manufacturing it and use thereof NIPPON SHOKUBAI CO., LTD. (JP) 2006-08-22 US disclosed
US-6914155-B2 High polymer gel and activation method for compounds containing active hydrogen NIPPON SHOKUBAI CO., LTD. (JP) 2005-07-05 US disclosed
US-20040087727-A1 Crosslinked polymer, method for manufacturing it and use thereof NIPPON SHOKUBAI CO., LTD. 2004-05-06 US disclosed
US-6646083-B2 Such as diallyldimethylammonium chloride crosslinked with 1,3-bis(N,N-diallylpiperid-1-ium-4-yl) propane dichloride; thermal stability; use as polymer catalyst for producing glycols from oxiranes; ion exchange catalyst NIPPON SHOKUBAI CO., LTD. (JP) 2003-11-11 US disclosed
US-20020028887-A1 Crosslinked polymer, method for manufacturing it and use thereof NIPPON SHOKUBAI CO., LTD. (JP) 2002-03-07 US disclosed
US-20020028872-A1 High polymer gel and activation method for compounds containing active hydrogen NIPPON SHOKUBAI CO., LTD. 2002-03-07 US disclosed
EP-0970937-A1 POLYMER GEL AND PROCESS FOR THE ACTIVATION OF ACTIVE HYDROGEN COMPOUNDS Nippon Shokubai Co., Ltd. (JP) 2000-01-12 EP disclosed