Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | CKS1B | P61024 | 4/20 | 0.63 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.63 |
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29575795 | 0.84 | KMT2A (1.00) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL1505430 | 0.84 | KMT2A (1.00) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL7197593 | 0.78 | SLC40A1 (1.00) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL13633886 | 0.78 | MEN1 (1.00) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL17506531 | 0.78 | CKS1B (1.00) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL22076984 | 0.76 | MEN1 (1.00) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL22111633 | 0.75 | MEN1 (0.84) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL4489851 | 0.75 | MEN1 (0.84) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL17506539 | 0.75 | KMT2A (0.79) | KMT2ATDP1MEN1LMNAMAPT | |
| SCHEMBL29800829 | 0.73 | GLO1 (0.78) | KMT2ATDP1MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275943-A1 | Method and Composition for Treatment or Prophylaxis of Amyloidosis Disorders | ACRUX DDS PTY LTD. | 2007-11-29 | — | — | US | claimed |
| EP-1684761-A1 | METHOD AND COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF AMYLOIDOSIS DISORDERS | Acrux DDS Pty Ltd (AU) | 2006-08-02 | — | — | EP | claimed |
| WO-2005049026-A1 | METHOD AND COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF AMYLOIDOSIS DISORDERS | ACRUX DDS PTY LTD (AU) | 2005-06-02 | — | — | WO | claimed |
| WO-2014062424-A1 | FLOWABLE FORMULATIONS FOR TISSUE REPAIR AND REGENERATION | TISSUE REPAIR COMPANY (US) | 2014-04-24 | — | — | WO | disclosed |
| US-20130096064-A1 | FLOWABLE FORMULATIONS FOR TISSUE REPAIR AND REGENERATION | TISSUE REPAIR COMPANY (US) | 2013-04-18 | — | — | US | disclosed |
| US-20070275943-A1 | Method and Composition for Treatment or Prophylaxis of Amyloidosis Disorders | ACRUX DDS PTY LTD. | 2007-11-29 | — | — | US | disclosed |
| EP-1684761-A1 | METHOD AND COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF AMYLOIDOSIS DISORDERS | Acrux DDS Pty Ltd (AU) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049026-A1 | METHOD AND COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF AMYLOIDOSIS DISORDERS | ACRUX DDS PTY LTD (AU) | 2005-06-02 | — | — | WO | disclosed |