Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501718 | 0.82 | ALDH1A1 (0.44) | DPP4DPP8ALDH1A1MAPK1TSHR | |
| SCHEMBL5598216 | 0.79 | DPP4 (0.35) | DPP4DPP8ALDH1A1TSHRTDP1 | |
| SCHEMBL28099521 | 0.72 | DPP4 (0.33) | DPP4DPP8 | |
| SCHEMBL5376614 | 0.72 | ALDH1A1 (0.48) | DPP4ALDH1A1MAPK1TSHRTDP1 | |
| SCHEMBL2048441 | 0.71 | PDCD1 (0.37) | DPP4DPP8ALDH1A1MAPK1TSHR | |
| SCHEMBL27748034 | 0.71 | USP7 (0.34) | — | |
| SCHEMBL28424180 | 0.70 | MAOB (0.38) | ALDH1A1MAPK1TSHRTDP1MEN1 | |
| SCHEMBL28776819 | 0.70 | DPP4 (0.40) | DPP4DPP8 | |
| SCHEMBL27748036 | 0.70 | PTGS2 (0.31) | DPP4PDCD1CD274 | |
| SCHEMBL8680603 | 0.69 | PDCD1 (0.41) | ALDH1A1TSHRTDP1ESR2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199274-B2 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2007-04-03 | — | — | US | disclosed |
| US-20050256344-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
| EP-1554233-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037756-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256344-A1 | Preparation of substituted indenes | CYP1A2, CYP1B1, DHPS | DPP4 4638/4885DPP8 4407/4885ALDH1A1 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.