Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598440 | 0.96 | LTA4H (0.32) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL1465968 | 0.84 | TDP1 (0.38) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL195629 | 0.82 | LTA4H (0.43) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL7615332 | 0.80 | LTA4H (0.41) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL3628714 | 0.79 | LTA4H (0.33) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL3628711 | 0.79 | LTA4H (0.33) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL1466000 | 0.79 | LTA4H (0.33) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL195903 | 0.77 | LTA4H (0.43) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL17189423 | 0.77 | CYP3A4 (0.43) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL28048701 | 0.76 | LTA4H (0.38) | LTA4HTSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179946-B2 | Copper complexes and their use | LANXESS DEUTSCHLAND GMBH (DE) | 2007-02-20 | — | — | US | disclosed |
| US-20040198997-A1 | Copper complexes and their use | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198997-A1 | Copper complexes and their use | SOD1, SOD3, ITPA | LTA4H 3598/4885TSHR 3515/4885CYP3A4 1213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.