Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592389 | 0.86 | DRD2 (0.39) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 | |
| SCHEMBL5592318 | 0.82 | MEN1 (0.36) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 | |
| SCHEMBL5592325 | 0.82 | NCF1 (0.36) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 | |
| SCHEMBL5745894 | 0.80 | BRD9 (0.39) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 | |
| SCHEMBL5592174 | 0.80 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 | |
| SCHEMBL5592291 | 0.79 | BRD9 (0.38) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 | |
| Hydrochloric Acid SCHEMBL6408358 | 0.79 | BRD9 (0.38) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 | |
| SCHEMBL22410991 | 0.74 | ROCK2 (0.41) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 | |
| SCHEMBL6434969 | 0.73 | ROCK2 (0.44) | SLC6A2HTR1ABRD9BRPF1DRD2 | |
| Citric Acid SCHEMBL6405366 | 0.72 | MC4R (0.34) | SLC6A2SLC6A4SLC6A3HTR1ABRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057742-A2 | NOVEL PIPERAZINONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |