Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 12/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599439 | 0.82 | GNRHR (0.37) | AGTR2GNRHRKCNH2 | |
| SCHEMBL5599096 | 0.81 | GNRHR (0.41) | GNRHRKCNH2MEN1KMT2A | |
| SCHEMBL5599816 | 0.80 | TP53 (0.38) | GNRHRKCNH2MEN1KMT2A | |
| SCHEMBL4761712 | 0.72 | BCHE (0.33) | GNRHRKCNH2 | |
| SCHEMBL5599501 | 0.69 | KDM1A (0.37) | GNRHRKCNH2 | |
| SCHEMBL5780284 | 0.69 | NPC1 (0.37) | GNRHRKCNH2MEN1KMT2A | |
| SCHEMBL5782306 | 0.68 | HTR2A (0.40) | GNRHRKCNH2 | |
| SCHEMBL5781576 | 0.68 | ALDH1A1 (0.40) | GNRHRKCNH2MEN1KMT2A | |
| SCHEMBL4761766 | 0.68 | PAX8 (0.37) | — | |
| SCHEMBL5784243 | 0.68 | GNRHR (0.42) | GNRHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063745-A9 | NOVEL SPIROINDOLINE OR SPIROISOQUINOLINE COMPOUNDS, METHODS OF USE AND COMPOSITIONS THEREOF | ARENA PHARM INC (US) | 2007-02-01 | — | — | WO | claimed |