SCHEMBL560043

SCHEMBL560043

O=C(CS)OC(CO)CO

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
MAPK1 P28482 1/20 0.47
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PRKCA P17252 3/20 0.38
FAAH O00519 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36
PRKCD Q05655 1/20 0.36
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11610628 0.88 MAPT (0.38) MAPTMAPK1TSHRHSD17B10PRKCA
SCHEMBL332068 0.84 PRKCA (0.53) PRKCAPRKCEPRKCQPRKCD
SCHEMBL6243511 0.81 TSHR (0.43) MAPTMAPK1TSHRHSD17B10
SCHEMBL2227700 0.80 MAPT (0.53) MAPTMAPK1PRKCAFAAHALDH1A1
SCHEMBL2568907 0.78 MAPT (0.50) MAPTMAPK1PRKCAFAAHALDH1A1
SCHEMBL13901278 0.78 MAPT (0.61) MAPTMAPK1PRKCAFAAHALDH1A1
SCHEMBL15841683 0.78 MAPT (0.50) MAPTMAPK1PRKCAFAAHALDH1A1
SCHEMBL15327684 0.77
SCHEMBL110032 0.75
SCHEMBL97661 0.75 ALDH1A1 (0.46) TSHRHSD17B10PRKCAALDH1A1PRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 730 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120132978-A Raw material crushing device for pretreatment of glycerol mercaptoacetate 湖北省彦弘实业有限公司 2025-06-13 CN claimed
US-20250134791-A1 HETEROCYCLIC-DITHIOL CLICK CHEMISTRY NORTHEASTERN UNIVERSITY 2025-05-01 US claimed
WO-2024178529-A1 COLORANT COMPOSITION FOR DYEING KERATIN FIBERS AND KIT COMPRISING THE SAME L'OREAL (FR) 2024-09-06 WO claimed
WO-2024162257-A1 HAIR-SHAPE-IMPARTING METHOD 花王株式会社 2024-08-08 WO claimed
CN-115992203-B Method for constructing genome-wide hydroxymethylation capture sequencing library 生工生物工程(上海)股份有限公司 2024-07-26 CN claimed
CN-118064996-B Portable wear-resistant polyamide fiber fabric 比音勒芬服饰股份有限公司 2024-06-14 CN claimed
CN-118103023-A Retarder composition and dye set comprising same 莱雅公司 2024-05-28 CN claimed
CN-118064996-A Portable wear-resistant polyamide fiber fabric 比音勒芬服饰股份有限公司 2024-05-24 CN claimed
CN-117860615-A Covalent treatment of keratin-containing materials 生活实验公司 2024-04-12 CN claimed
CN-117447773-A Biodegradable plastic and preparation method thereof 资阳众诺诚塑料制品有限责任公司 2024-01-26 CN claimed
EP-0363057-A2 Permanent wave solution REDKEN LABORATORIES INC. (US) 1990-04-11 EP claimed
US-4840791-A REDUCING HAIR DAMAGE REDKEN LABORATORIES, INC. (US) 1989-06-20 US claimed
EP-0027588-B1 METHOD FOR THE STABILIZATION OF PVC MOULDING MASSES AND MEANS FOR CARRYING OUT THE METHOD, AND ARTICLES PRODUCED THEREWITH NEYNABER CHEMIE GmbH (DE) 1989-03-15 EP claimed
US-4675181-A GERMANIUM, ANTIMONY AND BISMUTH COMPOUNDS TO COUN TERACT HYDROGEN SULFIDE SAN-EI KAGAKU CO. (JP) 1987-06-23 US claimed
US-4659566-A Compositions and methods for permanently waving or straightening hair BRITISH TECHNOLOGY GROUP LIMITED (GB) 1987-04-21 US claimed
EP-0191825-A1 COMPOSITIONS AND METHODS FOR PERMANENTLY WAVING OR STRAIGHTENING HAIR Petrow, Henry (US) 1986-08-27 EP claimed
WO-1986001403-A1 COMPOSITIONS AND METHODS FOR PERMANENTLY WAVING OR STRAIGHTENING HAIR PETROW HENRY G 1986-03-13 WO claimed
US-4548811-A COMPRISING A MERCAPTO AND A CYCLODEXTRIN-CARBO KETONE INCLUSION CO SHISEIDO COMPANY LTD. (JP) 1985-10-22 US claimed
US-4547365-A CYCLODEXTRINS AND ALDEHYDE OR KETONE COMPOUNDS; ODORLESS SHISEIDO COMPANY LTD. (JP) 1985-10-15 US claimed
US-4424820-A SODIUM HYDROXIDE, REDUCING AGENT REDKEN LABORATORIES, INC. (US) 1984-01-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250134791-A1 HETEROCYCLIC-DITHIOL CLICK CHEMISTRY TST, TMT1A, MTHFD2 MAPT 1727/4885MAPK1 2886/4885TSHR 2717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.