SCHEMBL2227700

SCHEMBL2227700

O=C(CCS)OC(CO)CO

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
MAPK1 P28482 1/20 0.53
FAAH O00519 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
PRKCA P17252 4/20 0.42
PRKCE Q02156 2/20 0.42
PRKCQ Q04759 2/20 0.42
PRKCD Q05655 2/20 0.42
ACE P12821 1/20 0.41
MGLL Q99685 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538145 0.86 PRKCA (0.60) MAPTMAPK1ALDH1A1PRKCAPRKCE
SCHEMBL13901278 0.85 MAPT (0.61) MAPTMAPK1FAAHALDH1A1HPGD
SCHEMBL25272484 0.81 ACE (0.41) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL560043 0.80 MAPT (0.47) MAPTMAPK1FAAHALDH1A1HPGD
SCHEMBL99261 0.77 ALDH1A1 (0.56) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL76959 0.76 MAPT (0.70) MAPTMAPK1FAAHALDH1A1HPGD
SCHEMBL8843449 0.76 MAPT (0.64) MAPTMAPK1FAAHALDH1A1HPGD
SCHEMBL542358 0.76 MAPT (0.53) MAPTMAPK1FAAHALDH1A1HPGD
SCHEMBL25475240 0.76 ACE (0.38) MAPTMAPK1ALDH1A1PRKCAPRKCE
SCHEMBL29225303 0.75 ACE (0.43) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12458576-B2 Method for removing color from artificially colored hair L'OREAL (FR) 2025-11-04 US claimed
US-20240122833-A1 METHOD FOR REMOVING COLOR FROM ARTIFICIALLY COLORED HAIR L'OREAL (FR) 2024-04-18 US claimed
EP-3506877-B1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS LABORATOIRE BIOSTHETIQUE KOSMETIK GMBH & CO KG (DE) 2024-03-27 EP claimed
US-20230355496-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS LABORATOIRE BIOSTHETIQUE KOSMETIK GMBH & CO. KG (DE) 2023-11-09 US claimed
EP-3773439-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2021-02-17 EP claimed
US-20210030651-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2021-02-04 US claimed
CN-111936111-A Hair treatment composition comprising a reducing agent 欧莱雅 2020-11-13 CN claimed
WO-2020220098-A1 STABLE HAIR TREATMENT COMPOSITIONS COMPRISING THIOL-BASED REDUCING AGENTS AND CHELATING AGENTS L'OREAL (FR) 2020-11-05 WO claimed
WO-2020061659-A1 STABLE HAIR TREATMENT COMPOSITIONS COMPRISING THIOL-BASED REDUCING AGENTS L'OREAL (FR) 2020-04-02 WO claimed
WO-2019195900-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2019-10-17 WO claimed
WO-2019195901-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2019-10-17 WO claimed
WO-2019197852-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2019-10-17 WO claimed
EP-3506877-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS Laboratoire Biosthetique Kosmetik GmbH&Co. KG (DE) 2019-07-10 EP claimed
US-20190201306-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS LABORATORIE BIOSTHETIQUE KOSMETIK GMBH & CO. KG (DE) 2019-07-04 US claimed
WO-2018042228-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS LABORATOIRE BIOSTHETIQUE KOSMETIK GMBH & CO. KG (DE) 2018-03-08 WO claimed
EP-3893834-B1 STRAIGHTENING PROCESS FOR KERATIN FIBERS OREAL (FR) 2026-04-29 EP disclosed
US-12491146-B1 Skin brightening compositions with thiopyridinone compound L'OREAL (FR) 2025-12-09 US disclosed
EP-2568848-A1 HAIR TREATMENT METHOD L'Oréal (FR) 2013-03-20 EP disclosed
WO-2011141882-A1 HAIR TREATMENT METHOD L'OREAL (FR) 2011-11-17 WO disclosed
WO-2011089985-A1 COSMETIC COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2011-07-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458576-B2 Method for removing color from artificially colored hair TYR, COXFA4L2, CAT MAPT 4298/4885MAPK1 2554/4885FAAH 4217/4885
US-20210030651-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS TST, DSG1, TYR MAPT 1931/4885MAPK1 3565/4885FAAH 3646/4885
US-20230355496-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS KRT18, CUTA, CRYAA MAPT 226/4885MAPK1 2150/4885FAAH 3589/4885
US-12491146-B1 Skin brightening compositions with thiopyridinone compound GLMN, GNMT, GLA MAPT 2938/4885MAPK1 3653/4885FAAH 4273/4885
US-20240122833-A1 METHOD FOR REMOVING COLOR FROM ARTIFICIALLY COLORED HAIR TYR, COXFA4L2, CAT MAPT 4298/4885MAPK1 2554/4885FAAH 4217/4885
US-20190201306-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS KRT18, CUTA, CRYAA MAPT 226/4885MAPK1 2150/4885FAAH 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.