SCHEMBL5602957

SCHEMBL5602957

C1=C(n2cccc2)CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601172 1.00 MAPK1 (0.32) MAPK1LMNAMAPT
SCHEMBL5603589 1.00 MAPK1 (0.32) MAPK1LMNAMAPT
SCHEMBL5602657 1.00 MAPK1 (0.32) MAPK1LMNAMAPT
SCHEMBL5601494 0.98 LMNA (0.33) LMNAMAPT
SCHEMBL5600749 0.91 LMNA (0.37) MAPK1LMNAMAPT
SCHEMBL28785176 0.78
SCHEMBL2073935 0.71 CYP11B2 (0.42) LMNAMAPT
SCHEMBL23661069 0.70 ALDH1A1 (0.35) LMNAMAPT
SCHEMBL22806637 0.70 ALDH1A1 (0.35) LMNAMAPT
SCHEMBL11110396 0.70 ALDH1A1 (0.35) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed