SCHEMBL560106

SCHEMBL560106

CC(C)(C)OC(=O)C(N)CN1CCNCC1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PADI1 Q9ULC6 2/20 0.41
PADI4 Q9UM07 2/20 0.41
CHRM5 P08912 1/20 0.41
CHRM3 P20309 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
SIGMAR1 Q99720 2/20 0.38
ANPEP P15144 1/20 0.35
ERAP2 Q6P179 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
NR1H2 P55055 1/20 0.32
MAPT P10636 1/20 0.32
DPP4 P27487 1/20 0.31
NOS1 P29475 2/20 0.31
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL485946 0.84 ANPEP (0.42) SIGMAR1ANPEPERAP2MEN1KMT2A
SCHEMBL7361998 0.83 TSHR (0.38) SMN1; SMN2KMT2AALDH1A1DPP4
SCHEMBL31138116 0.83 USP2 (0.47) SMN1; SMN2ANPEPMEN1KMT2AALDH1A1
SCHEMBL31503050 0.82 MEN1 (0.39) PADI1PADI4CHRM5CHRM3SMN1; SMN2
SCHEMBL31503051 0.82 MEN1 (0.39) PADI1PADI4CHRM5CHRM3SMN1; SMN2
SCHEMBL7501509 0.80 CHRM2 (0.40) CHRM3ALDH1A1KDM4EDPP4
SCHEMBL18205337 0.80 SMN1; SMN2 (0.38) PADI1PADI4CHRM5CHRM3SMN1; SMN2
SCHEMBL28706595 0.80 SMN1; SMN2 (0.38) PADI1PADI4CHRM5CHRM3SMN1; SMN2
SCHEMBL939405 0.74 CHRM5 (0.41) PADI1PADI4CHRM5CHRM3SMN1; SMN2
SCHEMBL26912060 0.74 CHRM5 (0.41) PADI1PADI4CHRM5CHRM3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
EP-4737898-A2 SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE EMP Biotech GmbH (DE) 2026-05-06 EP disclosed
EP-4304842-B1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC (CH) 2026-05-06 EP disclosed
US-20260042797-A1 SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE EMP BIOTECH GMBH (DE) 2026-02-12 US disclosed
US-12344633-B2 Separation and isolation of nucleic acids using affinity ligands bound to a solid surface EMP BIOTECH GMBH (DE) 2025-07-01 US disclosed
US-12297323-B2 Polysiloxane vinylic crosslinkers with high refractive index ALCON INC. (CH) 2025-05-13 US disclosed
EP-4314118-B1 POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX ALCON INC (CH) 2025-04-30 EP disclosed
US-12285922-B2 Method for making photofunctional contact lenses ALCON INC. (CH) 2025-04-29 US disclosed
US-12247169-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2025-03-11 US disclosed
EP-4313567-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2025-01-29 EP disclosed
US-7981885-B2 N-[3-substituted piperazino] alkylphenothiazines; antiproliferative agents, apoptotic agents; 5-HT receptor antagonists IMMUNE CONTROL INC. (US) 2011-07-19 US disclosed
US-7923445-B2 10-{3-[4-(2-Amino)ethylpiperazinyl]propyl}2-trifluoromethylphenothiazine and analogues and derivatives; antiproliferative agents; serotonin receptor antagonists; apoptosis in activated lymphocytes, including T, B, and and mylenoma cells; asthma; antiarthritic agents; rheumatic diseeases IMMUNE CONTROL, INC. (US) 2011-04-12 US disclosed
EP-2089391-A2 BRUTON'S TYROSINE KINASE ACTIVITY PROBE AND METHOD OF USING PHARMACYCLICS, INC. (US) 2009-08-19 EP disclosed
EP-2061788-A1 NOVEL COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES RELATED TO ACTIVATED LYMPHOCYTES Immune Control, Inc. (US) 2009-05-27 EP disclosed
US-20080214501-A1 Bruton's tyrosine kinase (Btk) activity probe comprising a Btk inhibitor moiety, a reporter moiety, and a linker moiety that links the inhibitor moiety to the reporter moiety; probes are used to characterize and develop Btk-selective inhibitors intended for therapeutic use PHARMACYCLICS, INC. (US) 2008-09-04 US disclosed
US-20080132697-A1 Novel compositions for treatment of diseases related to activated lymphocytes IMMUNE CONTROL, INC. (US) 2008-06-05 US disclosed
US-20080125415-A1 Novel methods for treatment of diseases related to activated lymphocytes IMMUNE CONTROL, INC. (US) 2008-05-29 US disclosed
WO-2008054827-A2 BRUTON'S TYROSINE KINASE ACTIVITY PROBE AND METHOD OF USING PHARMACYCLICS, INC. (US) 2008-05-08 WO disclosed
WO-2008027521-A1 NOVEL COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES RELATED TO ACTIVATED LYMPHOCYTES IMMUNE CONTROL, INC. (US) 2008-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344633-B2 Separation and isolation of nucleic acids using affinity ligands bound to a solid surface ADAR, SSBP1, POLRMT PADI1 3441/4885PADI4 3409/4885CHRM5 3581/4885
US-20080214501-A1 Bruton's tyrosine kinase (Btk) activity probe comprising a Btk inhibitor moiety, a reporter moiety, and a linker moiety that links the inhibitor moiety to the reporter moiety; probes are used to characterize and develop Btk-selective inhibitors intended for therapeutic use BTK, SYK, LYN PADI1 677/4885PADI4 783/4885CHRM5 4827/4885
US-20260042797-A1 SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE POLM, SSBP1, POLRMT PADI1 1602/4885PADI4 2213/4885CHRM5 1344/4885
US-20080132697-A1 Novel compositions for treatment of diseases related to activated lymphocytes NFATC1, CD4, TPH1 PADI1 3701/4885PADI4 2989/4885CHRM5 361/4885
US-20080125415-A1 Novel methods for treatment of diseases related to activated lymphocytes HTR5A, TPH1, TPH2 PADI1 2762/4885PADI4 1737/4885CHRM5 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.