Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | USP19 | O94966 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600097 | 1.00 | TDP1 (0.51) | TDP1CCKBRALDH1A1HTTUSP19 | |
| SCHEMBL5602170 | 0.85 | PABPC1 (0.46) | TDP1CCKBRUSP19PDE4APDE4B | |
| SCHEMBL2062436 | 0.85 | TDP1 (0.49) | TDP1ALDH1A1HTTUSP19MAPT | |
| SCHEMBL5600105 | 0.80 | TNF (0.45) | TDP1ALDH1A1MAPTCYP2C19ACHE | |
| SCHEMBL14870479 | 0.79 | USP19 (0.47) | TDP1ALDH1A1HTTUSP19MAPT | |
| SCHEMBL14928711 | 0.76 | TDP1 (0.45) | TDP1ALDH1A1HTTTSHRACHE | |
| SCHEMBL6925072 | 0.76 | ALDH1A1 (0.49) | TDP1ALDH1A1HTTMAPTPKM | |
| SCHEMBL6925075 | 0.76 | ALDH1A1 (0.49) | TDP1ALDH1A1HTTMAPTPKM | |
| SCHEMBL1529727 | 0.73 | ACHE (0.44) | ALDH1A1HTTUSP19MAPTPKM | |
| SCHEMBL1529729 | 0.73 | ACHE (0.44) | ALDH1A1HTTUSP19MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029076-A1 | ISOINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |