Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987789 | 0.93 | CYP1A2 (0.43) | CYP1A2CYP2A6TAAR1IDO1ACHE | |
| SCHEMBL558967 | 0.79 | TAAR1 (0.48) | CYP1A2CYP2A6TAAR1IDO1TDP1 | |
| SCHEMBL1141849 | 0.76 | TAAR1 (0.50) | CYP2A6TAAR1IDO1AGXTALDH1A1 | |
| SCHEMBL5953553 | 0.75 | LPL (0.45) | TAAR1ALDH1A1POLB | |
| SCHEMBL5954137 | 0.75 | BCHE (0.47) | CYP1A2ACHETP53LMNAPOLB | |
| SCHEMBL2291118 | 0.74 | ALDH1A1 (0.35) | TAAR1MAPTALDH1A1LMNACYP11B1 | |
| SCHEMBL5249994 | 0.74 | IDO1 (0.46) | CYP1A2CYP2A6TAAR1IDO1ACHE | |
| SCHEMBL5633593 | 0.74 | IDO1 (0.46) | CYP1A2CYP2A6TAAR1IDO1ACHE | |
| SCHEMBL467216 | 0.73 | TAAR1 (0.54) | TAAR1IDO1AGXTTP53MAPT | |
| SCHEMBL1006697 | 0.73 | CYP1A2 (0.37) | CYP1A2MAPTALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242747-A1 | MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | WO | claimed |
| US-7273948-B2 | Process of preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS, INC. (US) | 2007-09-25 | — | — | US | claimed |
| EP-1594824-A4 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | ATHEROGENICS INC (US) | 2007-04-04 | — | — | EP | claimed |
| EP-1594824-A2 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | Atherogenics, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| US-20040204485-A1 | Process of preparing esters and ethers of probucol and derivatives thereof | CRABTREE ACQUISITION CO, LLC | 2004-10-14 | — | — | US | claimed |
| WO-2004062622-A2 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | ATHEROGENICS, INC. (US) | 2004-07-29 | — | — | WO | claimed |
| WO-2025242747-A1 | MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | WO | disclosed |
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners (US) | 2025-04-01 | — | — | US | disclosed |
| CN-118527068-A | Tubular reactor capable of continuously producing Grignard reagent | 吉林化工学院 | 2024-08-23 | — | — | CN | disclosed |
| US-12049461-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2024-07-30 | — | — | US | disclosed |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| CN-112789108-B | Catalyst for asymmetric hydrogenation of compounds containing carbon double bonds | 格拉斯如睦株式会社 | 2023-09-19 | — | — | CN | disclosed |
| US-5190957-A | TREATMENT OF MULTI-DRUG RESISTANT TUMORS WITH QUINOLYL-AND ISOQUINOLYLOXAZOLE-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-02 | — | — | US | disclosed |
| WO-1991018007-A1 | PHTHALOCYANATOPOLYETHYLENE GLYCOL, AND PHTHALOCYANATO SACCHARIDES AS FLUORESCENT DIGOXIN REAGENTS | DIATRON CORPORATION (US) | 1991-11-28 | — | — | WO | disclosed |
| US-5061715-A | Useful in treating AIDS and ARC | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-29 | — | — | US | disclosed |
| US-4999431-A | Reacting A Bromoquinoline Compound With Butyllithium And An N-Methyl-N-Methoxyalkanamide; Intermediates for Quinolyloxazole-2-ones | MERRELL DOW PHARMACEUTICALS (US) | 1991-03-12 | — | — | US | disclosed |
| US-4990519-A | Antiasthma, hypotensive agents, bronchodilator agents | MERRELL DOW PHARMACEUTICALS (US) | 1991-02-05 | — | — | US | disclosed |
| US-4886811-A | HYPOTENSIVE AGENTS AND VASODILATORS | MERRELL DOW PHARMACEUTICALS (US) | 1989-12-12 | — | — | US | disclosed |
| US-4692515-A | BACTERICIDE, ANTICONVULSANT, ANTIHYPOXIA, ANTIPARKINSON, ANTICHOLINERGICS | PENNWALT CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12049461-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | NR3C1, NR3C2, NR4A1 | CYP1A2 1131/4885CYP2A6 1385/4885TAAR1 319/4885 |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | CYP1A2 848/4885CYP2A6 703/4885TAAR1 2099/4885 |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | CYP1A2 848/4885CYP2A6 703/4885TAAR1 2099/4885 |
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | CYP1A2 848/4885CYP2A6 703/4885TAAR1 2099/4885 |
| US-20040204485-A1 | Process of preparing esters and ethers of probucol and derivatives thereof | NR3C2, MGLL, GCG | CYP1A2 394/4885CYP2A6 355/4885TAAR1 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.