Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 4/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950339 | 0.82 | EED (0.50) | ALDH1A1 | |
| SCHEMBL27773492 | 0.81 | KDM1A (0.42) | CYP3A4 | |
| SCHEMBL3296090 | 0.81 | GLA (0.46) | ALDH1A1HPGDCALM1 | |
| SCHEMBL19923814 | 0.78 | PTPN1 (0.47) | AKR1B1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL29910924 | 0.73 | CA2 (0.58) | KMT2ACYP3A4 | |
| SCHEMBL19923816 | 0.70 | SHBG (0.66) | ALDH1A1TSHRCYP3A4LMNA | |
| SCHEMBL2200862 | 0.69 | ALDH1A1 (0.48) | ALDH1A1TSHRHPGDKMT2ACYP19A1 | |
| SCHEMBL16897961 | 0.69 | EED (0.51) | ALDH1A1TSHRAKR1B1L3MBTL1CYP19A1 | |
| 1,3,5-Trimethoxybenzene SCHEMBL28416912 | 0.68 | ALDH1A1 (0.92) | ALDH1A1CYP19A1CYP3A4 | |
| SCHEMBL19002612 | 0.68 | ALDH1A1 (0.41) | ALDH1A1TSHRKMT2AL3MBTL1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186834-B | New herbicides | SYNGENTA LTD | 2014-08-13 | — | — | CN | disclosed |
| US-8735322-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-05-27 | — | — | US | disclosed |
| EP-2350034-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| US-20120035053-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-09 | — | — | US | disclosed |
| EP-2350034-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010046194-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035053-A1 | NOVEL HERBICIDES | DDT, HCAR3, HPD | ALDH1A1 352/4885TSHR 1964/4885AKR1B1 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.