SCHEMBL5603597

SCHEMBL5603597

C=Cc1cc(OC)c(OC)cc1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
KDM4E B2RXH2 2/20 0.60
TSHR P16473 2/20 0.60
TDP1 Q9NUW8 2/20 0.60
CYP3A4 P08684 2/20 0.58
HMGCR P04035 1/20 0.58
NFE2L2 Q16236 1/20 0.50
CYP1A1 P04798 4/20 0.48
CYP1B1 Q16678 4/20 0.48
CYP1A2 P05177 3/20 0.48
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NOD2 Q9HC29 2/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
PRKDC P78527 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TRPA1 O75762 1/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15899630 0.95 ALDH1A1 (0.52) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL24239849 0.84 ALDH1A1 (0.43) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL24515188 0.84 ALDH1A1 (0.43) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL22651462 0.82 TRPA1 (0.48) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL12540073 0.81 ALDH1A1 (0.45) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL31607063 0.79 PRKDC (0.64) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL13538090 0.79 ALDH1A1 (0.43) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL13673038 0.79 ALDH1A1 (0.48) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL14135320 0.79 CYP3A4 (0.47) ALDH1A1KDM4ETSHRTDP1CYP3A4
SCHEMBL4092495 0.78 HMGCR (0.61) ALDH1A1KDM4ETSHRTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114709406-A Sulfur-rich copolymer material, lithium-sulfur battery positive electrode material, and preparation methods and applications thereof 中国电建集团成都勘测设计研究院有限公司 2022-07-05 CN claimed
CN-102126933-B Diphenyl propane lignan compound and preparation method thereof UNIV HUNAN 2013-03-20 CN claimed
CN-102126933-A Diphenyl propane lignan compound and preparation method thereof UNIV HUNAN 2011-07-20 CN claimed
CN-102060640-A Method for preparing diphenyl propane lignan compound UNIV HUNAN 2011-05-18 CN claimed
EP-4707264-A2 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS Verbio SE (DE) 2026-03-11 EP disclosed
EP-4122924-B1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS VERBIO SE (DE) 2025-11-19 EP disclosed
US-12065450-B2 Compounds and the use thereof in metathesis reactions VERBIO SE (DE) 2024-08-20 US disclosed
CN-114709406-B Sulfur-rich copolymer material, lithium sulfur battery positive electrode material, and preparation methods and applications thereof 中国电建集团成都勘测设计研究院有限公司 2023-07-25 CN disclosed
EP-4122924-A2 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS Verbio Vereinigte BioEnergie AG (DE) 2023-01-25 EP disclosed
US-20230013959-A1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS VERBIO SE (DE) 2023-01-19 US disclosed
US-11414446-B1 Compounds and the use thereof in metathesis reactions VERBIO VEREINIGTE BIOENERGIE AG 2022-08-16 US disclosed
CN-114709406-A Sulfur-rich copolymer material, lithium-sulfur battery positive electrode material, and preparation methods and applications thereof 中国电建集团成都勘测设计研究院有限公司 2022-07-05 CN disclosed
US-6989467-B2 Microwave induced process for the preparation of substituted 4-vinylphenols COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-01-24 US disclosed
EP-1575889-A1 A MICROWAVE INDUCED PROCESS FOR THE PREPARATION OF SUBSTITUTED 4-VINYLPHENOLS Council of Scientific and Industrial Research (IN) 2005-09-21 EP disclosed
WO-2004056733-A1 A MICROWAVE INDUCED PROCESS FOR THE PREPARATION OF SUBSTITUTED 4-VINYLPHENOLS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-07-08 WO disclosed
US-20040118673-A1 Microwave induced process for the preparation of substituted 4-vinylphenols COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 2004-06-24 US disclosed
US-6388081-B1 4-substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries LION BIOSCIENCE AG (DE) 2002-05-14 US disclosed
US-6262269-B1 4-Substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries TREGA BIOSCIENCES, INC. 2001-07-17 US disclosed
EP-0977989-A1 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 2000-02-09 EP disclosed
WO-1998034115-A1 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11414446-B1 Compounds and the use thereof in metathesis reactions PRMT6, CYP2D6, POR ALDH1A1 1286/4885KDM4E 2310/4885TSHR 1953/4885
US-12065450-B2 Compounds and the use thereof in metathesis reactions PRMT6, CYP2D6, POR ALDH1A1 1286/4885KDM4E 2310/4885TSHR 1953/4885
US-20230013959-A1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS PRMT6, CYP2D6, POR ALDH1A1 1286/4885KDM4E 2310/4885TSHR 1953/4885
US-20040118673-A1 Microwave induced process for the preparation of substituted 4-vinylphenols HPD, PGD, FPGS ALDH1A1 1265/4885KDM4E 439/4885TSHR 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.