Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632277 | 0.90 | SMN1; SMN2 (0.49) | ALDH1A1XDHSMN1; SMN2HSD17B10RAB9A | |
| Hydrochloric Acid SCHEMBL4064447 | 0.88 | SMN1; SMN2 (0.47) | ALDH1A1XDHSMN1; SMN2HSD17B10RAB9A | |
| Biphenyl SCHEMBL28349298 | 0.74 | XDH (0.40) | ALDH1A1XDHRAB9A | |
| Hydrochloric Acid SCHEMBL6791179 | 0.72 | L3MBTL1 (0.50) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL9204216 | 0.72 | ELANE (0.43) | HTT | |
| SCHEMBL8210477 | 0.71 | NR1H2 (0.45) | ALDH1A1HDAC6RAB9A | |
| SCHEMBL9798992 | 0.69 | FFAR1 (0.68) | FFAR1HDAC1FFAR4RAB9AHIF1A | |
| SCHEMBL19006636 | 0.69 | FFAR1 (0.73) | ALDH1A1FFAR1FFAR4KMT2AMEN1 | |
| SCHEMBL15416993 | 0.69 | RAB9A (0.82) | ALDH1A1XDHSMN1; SMN2HSD17B10HDAC6 | |
| SCHEMBL3788576 | 0.69 | POLB (0.55) | SMN1; SMN2RAB9AKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069271-A2 | PROCESS FOR THE PURIFICATION OF (S) -N- (L-CARBOXY-2-METHYL-PROP-1-YL) -N-PENTANOYL-N- [2' - (1H-TETRAZ0L-5-YL) BIPHENY L-4 -YLMETHYL] -AMINE (VALSARTAN) | ALEMBIC LIMITED (IN) | 2007-06-21 | — | — | WO | disclosed |
| WO-2005049587-A1 | PROCESS FOR PREPARATION OF BIPHENYL TETRAZOLE | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-02 | — | — | WO | disclosed |