SCHEMBL560391

SCHEMBL560391

Clc1cc(Cl)c(Cl)c(Cl)c1.Clc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.86

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.86
AHR P35869 10/20 0.63
CYP3A4 P08684 3/20 0.56
HSD17B10 Q99714 6/20 0.55
TSHR P16473 6/20 0.55
HPGD P15428 5/20 0.55
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
CASP1 P29466 1/20 0.47
RECQL P46063 1/20 0.47
TP53 P04637 1/20 0.47
CYP1B1 Q16678 1/20 0.46
MAPK1 P28482 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL358001 0.93 ALDH1A1 (1.00) ALDH1A1AHRCYP3A4HSD17B10TSHR
SCHEMBL28845466 0.86 ALDH1A1 (0.63) ALDH1A1AHRCYP3A4HSD17B10TSHR
SCHEMBL8165912 0.80 ALDH1A1 (0.75) ALDH1A1AHRCYP3A4HSD17B10TSHR
SCHEMBL4456478 0.80 ALDH1A1 (0.65) ALDH1A1AHRCYP3A4HSD17B10TSHR
Methoxymethane SCHEMBL28100007 0.80 ALDH1A1 (0.75) ALDH1A1AHRCYP3A4HSD17B10TSHR
SCHEMBL4452922 0.78 ALDH1A1 (0.61) ALDH1A1AHRCYP3A4HSD17B10TSHR
SCHEMBL4459925 0.78 AHR (1.00) ALDH1A1AHRCYP3A4HSD17B10TSHR
SCHEMBL27835679 0.78 ALDH1A1 (0.71) ALDH1A1AHRCYP3A4HSD17B10TSHR
SCHEMBL4453545 0.78 AHR (0.60) ALDH1A1AHRCYP3A4HSD17B10TSHR
SCHEMBL29624841 0.78 AHR (0.60) ALDH1A1AHRCYP3A4HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070299243-A1 POLY(ARYLENE ETHER) PROCESS AND COMPOSITION CITIBANK, N.A., AS COLLATERAL AGENT 2007-12-27 US claimed
WO-2007149658-A1 POLY (ARYLENE ETHER) AND PROCESS FOR PREPARING THEM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2007-12-27 WO claimed
EP-0643030-B1 Process for isolating m-dichlorobenzene from isomeric dichlorobenzene mixtures BAYER AG (DE) 1997-06-04 EP claimed
US-5436377-A Process for isolating M-dichlorobenzene from mixtures of dichlorobenzene isomers BAYER AKTIENGESELLSCHAFT (DE) 1995-07-25 US claimed
EP-0347888-A2 Silicone oil recovery UNION CARBIDE CORPORATION (US) 1989-12-27 EP claimed
US-4845190-A Process for preparing polyarylene sulfides with recovery of carboxylic acid TOSOH CORPORATION (JP) 1989-07-04 US claimed
US-4749817-A USING A SULFIDED PALLADIUM OR PLATINUM CATALYST; SELECTIVITY STANDARD CHLORINE OF DELAWARE, INC. (US) 1988-06-07 US claimed
EP-0071038-B1 PROCESS FOR THE PREPARATION OF 2-CHLORO-4-NITROTOLUENE BAYER AG (DE) 1984-06-06 EP claimed
US-3983816-A COMPOSITIONS FOR PRODUCING FLICKERING SIGNALS THIOKOL CORPORATION (US) 1976-10-05 US claimed
EP-4367166-A1 COMPOSITION AND METHOD FOR PRODUCING A TRANSPARENT THERMOPLASTIC POLYCARBONATE/POLYMETHYL METHACRYLATE MOULDING COMPOUND Covestro Deutschland AG (DE) 2024-05-15 EP disclosed
US-20240132661-A1 COMPOSITION AND PROCESS FOR PRODUCING A TRANSLUCENT THERMOPLASTIC POLYCARBONATE-POLYMETHYL METHACRYLATE MOLDING COMPOUND COVESTRO DEUTSCHLAND AG (DE) 2024-04-25 US disclosed
US-20230378467-A1 BINDER COMPOSITION FOR ALL-SOLID-STATE SECONDARY BATTERY, SLURRY COMPOSITION FOR ALL-SOLID-STATE SECONDARY BATTERY, SOLID ELECTROLYTE-CONTAINING LAYER, AND ALL-SOLID-STATE SECONDARY BATTERY ZEON CORPORATION (JP) 2023-11-23 US disclosed
EP-4263709-A1 COMPOSITION AND PROCESS FOR PRODUCING A TRANSLUCENT THERMOPLASTIC POLYCARBONATE-POLYMETHYL METHACRYLATE MOLDING COMPOUND Covestro Deutschland AG (DE) 2023-10-25 EP disclosed
EP-4234622-A1 BINDER COMPOSITION FOR ALL-SOLID-STATE SECONDARY BATTERIES, SLURRY COMPOSITION FOR ALL-SOLID-STATE SECONDARY BATTERIES, SOLID ELECTROLYTE-CONTAINING LAYER, AND ALL-SOLID-STATE SECONDARY BATTERY Zeon Corporation (JP) 2023-08-30 EP disclosed
US-3984484-A Distillation in Raschig-phenol process HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-10-05 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed
US-3944674-A Combating insects with o dimethoxymethylphenyl-N-methylcarbamate CIBA-GEIGY AG (CH) 1976-03-16 US disclosed
US-3942971-A Dithiophosphates and their use as herbicides CIBA-GEIGY AG (CH) 1976-03-09 US disclosed
US-3940412-A 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them CIBA-GEIGY AG (CH) 1976-02-24 US disclosed
US-3933858-A INSECTICIDES CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299243-A1 POLY(ARYLENE ETHER) PROCESS AND COMPOSITION PCBP1, AHR, PUF60 ALDH1A1 4147/4885AHR 2/4885CYP3A4 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.