Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31472630 | 0.70 | GAA (0.54) | ALDH1A1TDP1GAAKDM4ENPC1 | |
| SCHEMBL31472622 | 0.70 | GAA (0.54) | ALDH1A1TDP1GAAKDM4ENPC1 | |
| SCHEMBL24575404 | 0.69 | KDM4E (0.48) | ALDH1A1TDP1KDM4ETSHRNPC1 | |
| SCHEMBL23640556 | 0.69 | KDM4E (0.48) | ALDH1A1TDP1KDM4ETSHRNPC1 | |
| SCHEMBL29127134 | 0.69 | ALDH1A1 (0.41) | ALDH1A1TDP1GAATSHRNPC1 | |
| SCHEMBL17980366 | 0.69 | FUCA1 (0.41) | ALDH1A1TDP1TSHRNPC1RAB9A | |
| SCHEMBL6426049 | 0.69 | ALDH1A1 (0.41) | ALDH1A1TDP1GAAKDM4ETSHR | |
| SCHEMBL8523728 | 0.67 | THRB (0.61) | ALDH1A1TDP1GAAKDM4ENPC1 | |
| SCHEMBL1238556 | 0.66 | — | — | |
| SCHEMBL30887532 | 0.66 | ALDH1A1 (0.65) | ALDH1A1TDP1GAAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997482-B1 | MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME | NIPPON ZEON CO (JP) | 2007-01-17 | — | — | EP | disclosed |
| US-6346581-B1 | CURABLE COMPOSITION COMPRISING POLYMER OBTAINED BY INTRODUCING FUNCTIONAL GROUP INTO CYCLOOLEFIN ADDITION POLYMER CONSISTING OF UNITS DERIVED FROM CYCLOOLEFIN MONOMERS WITH AND WITHOUT SIDE CHAIN HAVING 4 OR MORE CARBONS, HARDENING AGENT | NIPPON ZEON CO., LTD (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-0997482-A1 | MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME | NIPPON ZEON CO., LTD. (JP) | 2000-05-03 | — | — | EP | disclosed |