SCHEMBL5604595

SCHEMBL5604595

COc1ccc(C(OCC[C@H](C)O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 4/20 0.49
SLC6A1 P30531 2/20 0.49
KIF11 P52732 8/20 0.46
MEN1 O00255 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
KMT2A Q03164 1/20 0.44
SLC6A12 P48065 1/20 0.44
SLC6A13 Q9NSD5 1/20 0.44
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5604514 1.00 SLC6A11 (0.49) SLC6A11SLC6A1KIF11MEN1TP53
SCHEMBL5967855 1.00 SLC6A11 (0.49) SLC6A11SLC6A1KIF11MEN1TP53
SCHEMBL4533570 0.89 KIF11 (0.53) SLC6A11SLC6A1KIF11CYP2C9ALOX15
SCHEMBL5899878 0.89 KIF11 (0.53) SLC6A11SLC6A1KIF11CYP2C9ALOX15
SCHEMBL6749203 0.89 KIF11 (0.53) SLC6A11SLC6A1KIF11CYP2C9ALOX15
SCHEMBL28350118 0.85 SLC6A11 (0.46) SLC6A11SLC6A1KIF11MEN1TP53
SCHEMBL24937040 0.85 LMNA (0.46) SLC6A11SLC6A1KIF11MEN1KMT2A
SCHEMBL10434128 0.85 LMNA (0.46) SLC6A11SLC6A1KIF11MEN1KMT2A
SCHEMBL10434091 0.85 LMNA (0.46) SLC6A11SLC6A1KIF11MEN1KMT2A
SCHEMBL8633174 0.85 KIF11 (0.48) SLC6A11SLC6A1KIF11MEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070015927-A1 New phosphoramidite compounds POSTECH FOUNDATION (KR) 2007-01-18 US disclosed
US-20070015927-A1 New phosphoramidite compounds POSTECH FOUNDATION (KR) 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015927-A1 New phosphoramidite compounds TYMP, POLRMT, POLI SLC6A11 4267/4885SLC6A1 4608/4885KIF11 2402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.