Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759107 | 0.86 | L3MBTL1 (0.50) | HSD11B1PDE3BPDE3AHTR1AHTR7 | |
| SCHEMBL11928135 | 0.84 | L3MBTL1 (0.57) | HSD11B1PDE3BPDE3ADRD3HTR4 | |
| SCHEMBL26511515 | 0.83 | GNAI3 (0.56) | HSD11B1HTR4 | |
| SCHEMBL5605766 | 0.82 | L3MBTL1 (0.49) | ALDH1A1HTR1AHTR7ATMSMN1; SMN2 | |
| SCHEMBL11923454 | 0.82 | HSD11B1 (0.45) | HSD11B1PDE3BPDE3AHTR1AHTR7 | |
| SCHEMBL11106 | 0.81 | HSD11B1 (0.44) | HSD11B1PDE3BPDE3AHTR1AHTR7 | |
| SCHEMBL16353682 | 0.80 | TSHR (0.55) | HSD11B1ALDH1A1HTR1AHTR7ATM | |
| SCHEMBL12395531 | 0.78 | DRD3 (0.61) | HSD11B1ALDH1A1PDE3BPDE3APOLB | |
| SCHEMBL5605768 | 0.78 | HSD11B1 (0.53) | HSD11B1ALDH1A1HTR1AHTR7ATM | |
| SCHEMBL9029279 | 0.78 | HTR1A (0.43) | HSD11B1PDE3BPDE3AHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166594-B2 | Antibacterial activity | AVENTIS PHARMA S.A. (FR) | 2007-01-23 | — | — | US | disclosed |
| US-20030149004-A1 | Streptogramin derivatives, their preparation and compositions containing them | AVENTIS PHARMA S.A. | 2003-08-07 | — | — | US | disclosed |
| US-6569854-B1 | Virginamycins | AVENTIS PHARMA S.A. (FR) | 2003-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149004-A1 | Streptogramin derivatives, their preparation and compositions containing them | MRPL21, ABHD5, APEH | HSD11B1 530/4885ALDH1A1 4296/4885PDE3B 1711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.