Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 2/20 | 0.30 |
| ▸ | EDNRA | P25101 | 2/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6905950 | 0.86 | KMO (0.34) | ALOX5MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL820362 | 0.80 | ALDH1A1 (0.32) | SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL820471 | 0.74 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL4092756 | 0.74 | MAOA (0.33) | KDM1AKDM1BALOX5MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4059545 | 0.74 | MAOA (0.33) | KDM1AKDM1BALOX5MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4094393 | 0.74 | MAOA (0.33) | KDM1AKDM1BALOX5MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18112870 | 0.73 | ESR1 (0.33) | KDM1AKDM1BALOX5MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27505811 | 0.73 | MAOA (0.32) | KDM1AKDM1BALOX5MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5606827 | 0.72 | KDM4E (0.31) | KDM1AKDM1BSMN1; SMN2KDM4EEDNRB | |
| SCHEMBL27479178 | 0.72 | MAOA (0.34) | KDM1AKDM1BALOX5MAPTEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790917-B2 | POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020198340-A1 | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-26 | — | — | US | disclosed |