Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UQCRB | P14927 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 8/20 | 0.56 |
| ▸ | MMP9 | P14780 | 5/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | FGB | P02675 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607316 | 1.00 | UQCRB (0.58) | UQCRBMMP2MMP9ADAMTS4HDAC1 | |
| SCHEMBL20715878 | 0.92 | HDAC1 (0.62) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL19234913 | 0.92 | HDAC1 (0.62) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5078465 | 0.92 | HDAC1 (0.62) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL872212 | 0.87 | PKM (0.54) | MMP2MMP9ADAMTS4HDAC1MEN1 | |
| SCHEMBL27734638 | 0.87 | ALDH1A1 (0.55) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27734636 | 0.87 | ALDH1A1 (0.55) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7359876 | 0.86 | HTR6 (0.55) | MMP2MMP9ADAMTS4HDAC1POLB | |
| SCHEMBL19234892 | 0.86 | POLB (0.57) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5608211 | 0.86 | CES1 (0.58) | MMP2HDAC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238669-A1 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY | 2007-10-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238669-A1 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS | GLP1R, GIPR, IAPP | UQCRB 4252/4885MMP2 1305/4885MMP9 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.