SCHEMBL560750

SCHEMBL560750

Oc1ccc(Cl)cc1C1CCCC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 3/20 0.51
NUDT1 P36639 1/20 0.51
BACE1 P56817 1/20 0.51
PTGDR2 Q9Y5Y4 8/20 0.50
PTGDR Q13258 5/20 0.50
PTGER2 P43116 1/20 0.49
HSD17B10 Q99714 4/20 0.45
TSHR P16473 3/20 0.45
THRB P10828 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 1/20 0.42
AGTR1 P30556 1/20 0.42
HPGD P15428 3/20 0.42
ALOX15 P16050 3/20 0.42
ALDH1A1 P00352 3/20 0.42
ALOX12 P18054 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPK1 P28482 1/20 0.42
CYP3A4 P08684 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29729512 1.00 HSP90AA1 (0.51) HSP90AA1NUDT1BACE1PTGDR2PTGDR
SCHEMBL561154 0.98 NUDT1 (0.54) HSP90AA1NUDT1BACE1PTGDR2PTGDR
SCHEMBL4878435 0.98 NUDT1 (0.54) HSP90AA1NUDT1BACE1PTGDR2PTGDR
Potassium SCHEMBL29827419 0.98 HSP90AA1 (0.54) HSP90AA1NUDT1BACE1PTGDR2PTGDR
Water SCHEMBL6531551 0.96 NUDT1 (0.53) HSP90AA1NUDT1BACE1PTGDR2PTGDR
SCHEMBL12611071 0.92 HSD17B10 (0.48) HSP90AA1NUDT1BACE1PTGDR2PTGDR
Parachlorophenol SCHEMBL7605939 0.91 NUDT1 (0.49) HSP90AA1NUDT1BACE1PTGDR2PTGDR
SCHEMBL1104983 0.83 QDPR (0.51) HSD17B10TSHRMEN1KMT2AMAPK1
SCHEMBL27851437 0.82 PTGDR2 (0.48) HSP90AA1NUDT1BACE1PTGDR2PTGDR
Bromide SCHEMBL1095262 0.82 QDPR (0.50) HSD17B10TSHRMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0969846-B2 COMPOSITIONS AND METHODS FOR REDUCING OCULAR HYPERTENSION NOVARTIS AG (CH) 2010-08-25 EP claimed
EP-0969846-B1 COMPOSITIONS AND METHODS FOR REDUCING OCULAR HYPERTENSION NOVARTIS AG (CH) 2004-01-07 EP claimed
US-20020002185-A1 Compositions and methods for reducing ocular hypertension R-TECH UENO, LTD. (JP) 2002-01-03 US claimed
US-6066606-A MIXTURE OF TERPENE, SURFACTANT AND WATER RECKITT & COLMAN INC. (US) 2000-05-23 US claimed
CN-1249687-A Compositions and methods for reducing ocular hypertension NOVARTIS AG (CH) 2000-04-05 CN claimed
EP-0969846-A1 COMPOSITIONS AND METHODS FOR REDUCING OCULAR HYPERTENSION Novartis AG (CH) 2000-01-12 EP claimed
WO-1998041208-A1 COMPOSITIONS AND METHODS FOR REDUCING OCULAR HYPERTENSION NOVARTIS AG (CH) 1998-09-24 WO claimed
EP-0252278-B1 Disinfecting agents and their use in disinfecting the skin and mucous membranes HENKEL KGAA (DE) 1998-08-19 EP claimed
US-4900721-A Disinfectants and their use for disinfecting the skin and mucous membrane HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-02-13 US claimed
EP-0252278-A2 Disinfecting agents and their use in disinfecting the skin and mucous membranes Henkel Kommanditgesellschaft auf Aktien (DE) 1988-01-13 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4157977-A HYDROXYACETIC ACID, PHENOLIC DERIVATIVE, ANIONIC SURFACTANT CHEMED CORPORATION (US) 1979-06-12 US claimed
US-RE28778-E ANIONIC SURFACTANT WEST LABORATORIES, INC. (US) 1976-04-20 US claimed
US-20250024837-A1 PESTICIDE SYSTEM BANISH, MICHELE 2025-01-23 US disclosed
US-20240074434-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY HANSON (US) 2024-03-07 US disclosed
US-20240065262-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY HANSON (US) 2024-02-29 US disclosed
US-3873712-A Synergistic compositions for the control of aerobacter aerogenes BETZ LABORATORIES 1975-03-25 US disclosed
US-3873711-A Synergistic compositions for the control of aerobacter aerogenes BETZ LABORATORIES 1975-03-25 US disclosed
US-3873710-A Synergistic compositions for the control of aerobacter aerogenes BETZ LABORATORIES 1975-03-25 US disclosed
US-3862322-A SLIME CONTROL COMPOSITIONS AND THEIR USE BETZ LABORATORIES 1975-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250024837-A1 PESTICIDE SYSTEM ACHE, PFAS, FPGS HSP90AA1 4187/4885NUDT1 1855/4885BACE1 944/4885
US-20020002185-A1 Compositions and methods for reducing ocular hypertension PTGIS, PTGIR, PDE3A HSP90AA1 1735/4885NUDT1 1185/4885BACE1 4532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.