SCHEMBL5607684

SCHEMBL5607684

CCc1ccccc1OP(=O)(Oc1ccccc1CC)Sc1ccccc1CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
HPGD P15428 2/20 0.36
ATM Q13315 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
ACHE P22303 1/20 0.35
HTT P42858 2/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
KCNH2 Q12809 1/20 0.34
KDM4E B2RXH2 2/20 0.34
PTGS2 P35354 2/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5552764 0.87 L3MBTL1 (0.41) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL258521 0.86 HTR1A (0.38) NISCHSMN1; SMN2LMNAADRA2AADRA2B
SCHEMBL258595 0.83 THRA (0.40) PTGS2
SCHEMBL11465910 0.83 L3MBTL1 (0.38) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL258333 0.81 KMT2A (0.39) L3MBTL1HPGDSMN1; SMN2LMNAHTT
SCHEMBL3477747 0.81 THRA (0.47) PTGS2
SCHEMBL284750 0.81 THRA (0.47) PTGS2
SCHEMBL8600591 0.81 THRA (0.47) PTGS2
SCHEMBL3169769 0.80 HPGD (0.42) L3MBTL1HPGDNISCHSMN1; SMN2LMNA
SCHEMBL1605194 0.80 KCNH2 (0.45) L3MBTL1MAPTNPSR1HPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1405897-B1 USE OF A TRANSMISSION OIL FOR AUTOMOBILES NISSAN MOTOR (JP) 2013-06-26 EP disclosed
US-7307048-B2 comprises mineral oil, and phosphate compound selected a zinc dithiophosphate having hydrocarbon group, a triaryl phosphate, and triaryl thiophosphate; for electric motors; improved insulation, cooling and lubricity NISSAN MOTOR CO., LTD. (JP) 2007-12-11 US disclosed
US-20040209786-A1 comprises mineral oil, and phosphate compound selected a zinc dithiophosphate having hydrocarbon group, a triaryl phosphate, and triaryl thiophosphate; for electric motors; improved insulation, cooling and lubricity NIPPON OIL CORPORATION (JP) 2004-10-21 US disclosed
EP-1405897-A1 TRANSMISSION OIL COMPOSITION FOR AUTOMOBILE Nissan Motor Co., Ltd. (JP) 2004-04-07 EP disclosed