SCHEMBL258333

SCHEMBL258333

CC(C)Cc1ccccc1OP(=O)(Oc1ccccc1CC(C)C)Sc1ccccc1CC(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.39
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
FFAR4 Q5NUL3 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
HPGD P15428 3/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
P4HB P07237 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1788160 0.82 GABRA1 (0.42) KMT2AGABRA1GABRB2CTSSCTSK
SCHEMBL31271189 0.82 GABRA1 (0.42) KMT2AGABRA1GABRB2CTSSCTSK
SCHEMBL570428 0.82 ANPEP (0.39) KMT2AHTTL3MBTL1MEN1
SCHEMBL5607684 0.81 L3MBTL1 (0.41) SMN1; SMN2LMNAHTTL3MBTL1KDM4E
SCHEMBL258521 0.78 HTR1A (0.38) SMN1; SMN2LMNA
SCHEMBL28414567 0.76 INPPL1 (0.47) GABRA1GABRB2HTTKDM4EALDH1A1
SCHEMBL3832980 0.76 ANPEP (0.43) KMT2AGABRA1GABRB2HTTL3MBTL1
SCHEMBL15020257 0.76 ANPEP (0.43) KMT2AGABRA1GABRB2HTTL3MBTL1
SCHEMBL258595 0.75 THRA (0.40)
SCHEMBL3169769 0.75 HPGD (0.42) SMN1; SMN2LMNAL3MBTL1HPGDCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11946012-B2 Lubricating oil composition SHELL USA, INC. (US) 2024-04-02 US disclosed
US-20230002695-A1 LUBRICATING OIL COMPOSITION SHELL USA, INC. 2023-01-05 US disclosed
US-11254890-B2 Lubricant composition TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-02-22 US disclosed
WO-2021079976-A1 LUBRICATING OIL COMPOSITION FOR AUTOMOTIVE GEARS SHELL LUBRICANTS JAPAN K.K. (JP) 2021-04-29 WO disclosed
US-20210054299-A1 LUBRICANT COMPOSITION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2021-02-25 US disclosed
EP-2980194-B1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2020-04-01 EP disclosed
EP-2855645-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2019-08-14 EP disclosed
EP-2104728-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2018-10-24 EP disclosed
US-9410106-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2016-08-09 US disclosed
EP-2980194-A1 LUBRICANT OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2016-02-03 EP disclosed
US-20080318820-A1 Oil Composition for Use in Trace Oil Supply Cutting/Grinding Work NIPPON OIL CORPORATION (JP) 2008-12-25 US disclosed
US-20080026963-A1 Grease composition for one-way clutch NIPPON OIL CORPORATION (JP) 2008-01-31 US disclosed
EP-1867705-A1 GREASE COMPOSITION FOR ONE-WAY CLUTCH Nippon Oil Corporation (JP) 2007-12-19 EP disclosed
EP-1832647-A1 OIL COMPOSITION FOR USE IN TRACE OIL SUPPLY CUTTING / GRINDING WORK Nippon Oil Corporation (JP) 2007-09-12 EP disclosed
US-20070191240-A1 METAL WORKING FLUID NIPPON OIL CORPORATION (JP) 2007-08-16 US disclosed
US-20070179066-A1 Grease composition for constant velocity joint NIPPON OIL CORPORATION (JP) 2007-08-02 US disclosed
US-20070032391-A1 Refrigerating machine oil composition NIPPON OIL CORPORATION (JP) 2007-02-08 US disclosed
EP-1741771-A1 METALWORKING FLUID Nippon Oil Corporation (JP) 2007-01-10 EP disclosed
EP-1721957-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT Nippon Oil Corporation (JP) 2006-11-15 EP disclosed
EP-1702972-A1 METALWORKING FLUID Nippon Oil Corporation (JP) 2006-09-20 EP disclosed